{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T12:01:36Z","timestamp":1710763296194},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T00:00:00Z","timestamp":1383609600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Although effective in faecal incontinence (<jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content>), sacral nerve stimulation (<jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content>) is expensive and requires two procedures. It carries a small risk of infection and electrode migration. Transcutaneous <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> is noninvasive and cheap. Two small studies have reported the results when applied to segments S3 but there is no information on its effectiveness when applied to the whole sacral area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A pilot study was carried out of self\u2010administered transcutaneous <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> given over a 4\u2010week period for 12\u00a0h a day. A 2\u2010week bowel diary was kept for the final 2\u00a0weeks and compared with baseline. Patients were assessed using the St Mark's Incontinence Score, a visual analogue scale assessing satisfaction with bowel habit, the Rockwood <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content> Quality of Life (<jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content>) score and <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 10 patients recruited, two achieved complete continence. There was a statistically significant reduction in the median (interquartile range) frequency of incontinent episodes per week from 9.5 (7.5) to 3 (7.38) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.03), and in the median frequency of defaecation per week from 25.5 (19.5) to 14.5 (14.9) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.007). There was a statistically significant improvement in the median ability to defer defaecation from 1 (1.25) to 4.5 (4.5) min (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.02). There was also a statistically significant improvement in the St Marks Incontinence Score from 20 (5.25) to 14.5 (8.0) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.01) and in the bowel habit satisfaction visual analogue scale from 8.5 (20) to 45 (33) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.008). There was no change in the Rockwood <jats:styled-content style=\"fixed-case\">FI QOL<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> scores. No complications were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Transcutaneous <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> appears to be an effective and safe treatment for <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content>. Larger controlled studies are needed to explore this further.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12371","type":"journal-article","created":{"date-parts":[[2013,8,3]],"date-time":"2013-08-03T12:08:43Z","timestamp":1375531723000},"page":"1406-1409","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A pilot study of transcutaneous sacral nerve stimulation for faecal incontinence"],"prefix":"10.1111","volume":"15","author":[{"given":"G. P.","family":"Thomas","sequence":"first","affiliation":[{"name":"The Sir Alan Parks Department of Physiology St Mark's Hospital and Academic Institute Harrow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Norton","sequence":"additional","affiliation":[{"name":"The Sir Alan Parks Department of Physiology St Mark's Hospital and Academic Institute Harrow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J.","family":"Nicholls","sequence":"additional","affiliation":[{"name":"The Sir Alan Parks Department of Physiology St Mark's Hospital and Academic Institute Harrow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. J.","family":"Vaizey","sequence":"additional","affiliation":[{"name":"The Sir Alan Parks Department of Physiology St Mark's Hospital and Academic Institute Harrow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0593-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91799-3"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15999-0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02383.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182270af1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7302"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-010-1177-z"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-005-0068-3"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02586.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02229.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02236199"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.1.77"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6846.160"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e31827aed41"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2008.10.014"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.7748\/paed2003.04.15.3.20.c843"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.phm.0000247649.00219.c0"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02906.x"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.12371","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.12371","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T17:55:40Z","timestamp":1696269340000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.12371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/codi.12371"],"URL":"https:\/\/doi.org\/10.1111\/codi.12371","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"2013-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-04-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-11-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}