{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:44:31Z","timestamp":1790858671131,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,11,21]],"date-time":"2013-11-21T00:00:00Z","timestamp":1384992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The object of this study was to describe the course of <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ournier's gangrene and assess quality of life in a group of affected patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We evaluated patients who received inpatient treatment for <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ournier's gangrene at five hospitals in northern <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ermany from 1995 to 2010. Surviving patients were asked to take part in a clinical follow\u2010up and complete the <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>hort\u2010<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>orm 36 (<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036) quality\u2010of\u2010life questionnaire and a disease\u2010specific questionnaire including a physical examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 86 patients, 72 (83.7%) were men. The mean age of the patients was 57.9\u00a0\u00b1\u00a013.9 (25\u201389) years. The mean length of hospital stay was 52.0\u00a0\u00b1\u00a054.0 (1\u2013329) days. Fourteen (16.3%) patients (eight men) died primarily from Fournier's gangrene. The most common aetiological event was anogenital abscess formation (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>24; 27.9%). Seventy\u2010one (82.5%) patients had a mixed polymicrobial infection. <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 physical role functioning (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010), physical functioning (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.008), general health (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010) and physical health summary (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.006) scores were significantly lower than those of the normal population. Deterioration in sexual function was reported by 65% of the patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ournier's gangrene experience persistent physical and mental health problems for a long period of time following their primary hospital stay and must receive long\u2010term care from a variety of specialists, otherwise the disease leads to an increase in the duration of morbidity and a decrease in quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12396","type":"journal-article","created":{"date-parts":[[2013,8,27]],"date-time":"2013-08-27T07:49:02Z","timestamp":1377589742000},"page":"1529-1536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Treatment, outcome and quality of life after <scp>F<\/scp>ournier's gangrene: a multicentre study"],"prefix":"10.1111","volume":"15","author":[{"given":"R.","family":"Czymek","sequence":"first","affiliation":[{"name":"Department of General Visceral Vascular and Thoracic Surgery University of Luebeck Medical School Luebeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Kujath","sequence":"additional","affiliation":[{"name":"Department of General Visceral Vascular and Thoracic Surgery University of Luebeck Medical School Luebeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010P.","family":"Bruch","sequence":"additional","affiliation":[{"name":"Department of General Visceral Vascular and Thoracic Surgery University of Luebeck Medical School Luebeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Pfeiffer","sequence":"additional","affiliation":[{"name":"Department of Urology Asklepios Clinical Centre of Barmbek Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Nebrig","sequence":"additional","affiliation":[{"name":"Department of General Visceral and Transplantation Surgery Charit\u00e9 Hospital Humboldt University of Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Seehofer","sequence":"additional","affiliation":[{"name":"Department of General Visceral and Transplantation Surgery Charit\u00e9 Hospital Humboldt University of Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Guckelberger","sequence":"additional","affiliation":[{"name":"Department of General Visceral and Transplantation Surgery Charit\u00e9 Hospital Humboldt University of Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,21]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"589","article-title":"Gangrene foudroyante de la verge","volume":"4","author":"Fournier JA","year":"1883","journal-title":"Medecin Practique"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.08.050"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(96)80017-3"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)67236-7"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-010-0592-1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1001\/jama.1979.03290340021019","article-title":"Necrotizing fasciitis. 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