{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T19:35:38Z","timestamp":1772739338907,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,12]],"date-time":"2014-02-12T00:00:00Z","timestamp":1392163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Solitary rectal ulcer syndrome (<jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content>) is uncommon and its management is controversial. The aim of this study was to evaluate the outcome of patients with <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content> who underwent laparoscopic ventral rectopexy (<jats:styled-content style=\"fixed-case\">LVR<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A review was performed of a prospective database at the Oxford Pelvic Floor Centre to identify patients between 2004 and 2012 with a histological diagnosis of <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content>. All were initially treated conservatively and surgical treatment was indicated only for patients with significant symptoms after failed conservative management. The primary end\u2010point was healing of the ulcer. Secondary end\u2010points included changes in the Wexner Constipation Score and Faecal Incontinence Severity Index (<jats:styled-content style=\"fixed-case\">FISI<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six patients with <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content> were identified (31 women), with a median age of 44 (15\u201381) years. The commonest symptoms were rectal bleeding (75%) and obstructed defaecation (64%). The underlying anatomical diagnosis was internal rectal prolapse (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>20), external rectal prolapse (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>14) or anismus (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>2). Twenty\u2010nine patients underwent <jats:styled-content style=\"fixed-case\">LVR<\/jats:styled-content> and one a stapled transanal rectal resection (<jats:styled-content style=\"fixed-case\">STARR<\/jats:styled-content>) procedure. Nine (30%) required a further operation, six required posterior <jats:styled-content style=\"fixed-case\">STARR<\/jats:styled-content> for persistent <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content> and two a per\u2010anal stricturoplasty for a narrowing at the healed <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content> site. Healing of the <jats:styled-content style=\"fixed-case\">SRU<\/jats:styled-content> was seen in 27 (90%) of the 30 patients and was associated with significant improvements in Wexner and <jats:styled-content style=\"fixed-case\">FISI<\/jats:styled-content> scores at a 3\u2010year follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Almost all cases of <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content> in the present series were associated with rectal prolapse. <jats:styled-content style=\"fixed-case\">LVR<\/jats:styled-content> resulted in successful healing of the <jats:styled-content style=\"fixed-case\">SRUS<\/jats:styled-content> with good function in almost all patients, but a significant number will require further surgery such as <jats:styled-content style=\"fixed-case\">STARR<\/jats:styled-content> for persistent obstructed defaecation.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>\n<jats:boxed-text content-type=\"box\" position=\"anchor\"><jats:caption><jats:title>What does this paper add to the literature?<\/jats:title><\/jats:caption><jats:p>This study identifies a strong association between solitary rectal ulcer syndrome and advanced posterior compartment prolapse. It shows that laparoscopic ventral rectopexy to treat the prolapse results in healing of the ulcer with good bowel function in a high proportion of patients.<\/jats:p><\/jats:boxed-text>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12502","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T16:07:21Z","timestamp":1385395641000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Laparoscopic ventral rectopexy is effective for solitary rectal ulcer syndrome when associated with rectal prolapse"],"prefix":"10.1111","volume":"16","author":[{"given":"C.","family":"Evans","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Oxford Pelvic Floor Centre Oxford University Hospitals NHS Trust Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Oxford Pelvic Floor Centre Oxford University Hospitals NHS Trust Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O. 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