{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:29:53Z","timestamp":1761895793226},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T00:00:00Z","timestamp":1394755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Posterior tibial nerve stimulation (<jats:styled-content style=\"fixed-case\">PTNS<\/jats:styled-content>) has emerged in recent years as a therapy for faecal incontinence. Its long\u2010term effectiveness is yet to be established, along with what the form of retreatment should be in the event of loss of effectiveness. The present study aimed to establish the mid\u2010term results to identify the proportion of patients who may need further treatment, and if so when.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A prospective study including 30 patients was conducted at an academic hospital. The patients underwent 12 weekly outpatient treatment sessions, each lasting 30\u00a0min (first <jats:styled-content style=\"fixed-case\">PTNS<\/jats:styled-content> phase). Neuromodulation was discontinued in those patients who did not have a 40% decrease in their pretreatment Wexner score. Patients having a better than 40% response were offered another 12\u2010week course of complete treatment (second <jats:styled-content style=\"fixed-case\">PTNS<\/jats:styled-content> phase), following which they received no further <jats:styled-content style=\"fixed-case\">PTNS<\/jats:styled-content> treatment (phase without <jats:styled-content style=\"fixed-case\">PTNS<\/jats:styled-content>) but were assessed at 6\u00a0months and 2\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients finished the first phase and 22\/30 patients continued to the second phase. During this phase 11 patients showed an improved <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>exner score (baseline\/first phase\/second phase: 14.3\u00a0\u00b1\u00a04.2 <jats:italic>vs<\/jats:italic> 9.9\u00a0\u00b1\u00a05.4 <jats:italic>vs<\/jats:italic> 6.8\u00a0\u00b1\u00a05.4). After a 6\u2010month period without any treatment, the score was still improved in 11\/30 patients (9.1\u00a0\u00b1\u00a06.2). At 2\u00a0years there was improvement in 16\/30 patients (8.8\u00a0\u00b1\u00a07.1). There was a significant improvement in three variables of the quality of life questionnaire: lifestyle, coping behaviour and embarrassment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The response to first and second phase <jats:styled-content style=\"fixed-case\">PTNS<\/jats:styled-content> was maintained for up to 2\u00a0years. Retreatment was not required in about half of patients, even when they had finished the treatment 6\u00a0months or 2\u00a0years previously.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12539","type":"journal-article","created":{"date-parts":[[2013,12,21]],"date-time":"2013-12-21T06:46:43Z","timestamp":1387608403000},"page":"304-310","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Percutaneous neuromodulation of the posterior tibial nerve for the treatment of faecal incontinence \u2013 mid\u2010term results: is retreatment required?"],"prefix":"10.1111","volume":"16","author":[{"given":"F.","family":"de la Portilla","sequence":"first","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Laporte","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. V.","family":"Maestre","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"D\u00edaz\u2010Pav\u00f3n","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"Gollonet","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Palacios","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"V\u00e1zquez\u2010Monchul","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Garc\u00eda\u2010Cabrera","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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M.","family":"S\u00e1nchez Gil","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Cirug\u00eda General y del Aparato Digestivo Instituto de Biomedicina de Sevilla (IBIS) Hospital Universitario Virgen del Roc\u00edo\/CSIC\/Universidad de Sevilla Seville Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1272825"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.04.054"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-003-0114-6"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6180-6"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31823ac2bc"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01652.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02650.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e318227f65d"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02646.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00727-5"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000069399"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-007-0340-3"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181a7476a"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.02020.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181c75274"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588410X12628812459652"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-010-1085-4"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12093"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02906.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.03003.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20651"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e31828b6fd4"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.7748\/ns2011.02.25.24.44.c8343"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182a6266c"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.12539","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.12539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T14:30:40Z","timestamp":1695479440000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.12539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,14]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/codi.12539"],"URL":"https:\/\/doi.org\/10.1111\/codi.12539","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,14]]},"assertion":[{"value":"2013-07-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-11-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}