{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T06:29:09Z","timestamp":1768976949221,"version":"3.49.0"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,7,17]],"date-time":"2015-07-17T00:00:00Z","timestamp":1437091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Asociaci\u00f3n Espa\u00f1ola de Coloproctolog\u00eda","award":["2011"],"award-info":[{"award-number":["2011"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The management of rectal cancer threatening or affecting the prostatic plane is still under debate. The role of preoperative chemo radiotherapy and the extent of prostatectomy seem to be key points in the treatment of these tumours. The aim of the present study was to evaluate the pathological circumferential margin status and the local recurrence rate following different therapeutic options.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the status of the pathological circumferential resection margin (<jats:styled-content style=\"fixed-case\">CRM<\/jats:styled-content>) and local recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A consecutive series of 126 men with rectal cancer threatening (44) or affecting (82) the prostatic plane on preoperative staging and operated with local curative intent between 1998 and 2010 was analysed. In patients who did not have chemoradiotherapy but had a preoperative threatened anterior margin the <jats:styled-content style=\"fixed-case\">CRM<\/jats:styled-content>\u2010positive rate was 25.0%. In patients who did not have preoperative chemoradiotherapy but did have an affected margin, the <jats:styled-content style=\"fixed-case\">CRM<\/jats:styled-content>\u2010positive rate was 41.7%. When preoperative radiotherapy was given, the respective <jats:styled-content style=\"fixed-case\">CRM<\/jats:styled-content> infiltration rates were 7.1 and 20.7%. In patients having preoperative chemoradiotherapy followed by prostatic resection the rate of <jats:styled-content style=\"fixed-case\">CRM<\/jats:styled-content> positivity was 2.4%. Partial prostatectomy after preoperative chemoradiotherapy resulted in a free anterior <jats:styled-content style=\"fixed-case\">CRM<\/jats:styled-content> in all cases, but intra\u2010operative urethral damage occurred in 36.4% of patients who underwent partial prostatectomy, resulting in a postoperative urinary fistula in 18.2% of\u00a0patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Preoperative chemoradiation is mandatory in male patients with a threatened or affected anterior circumferential margin on preoperative <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. In patients with preoperative prostatic infiltration, prostatic resection is necessary. In this group of patients partial prostatectomy seems to be oncologically safe.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12933","type":"journal-article","created":{"date-parts":[[2015,3,2]],"date-time":"2015-03-02T19:25:33Z","timestamp":1425324333000},"page":"689-697","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate? 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