{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:47:38Z","timestamp":1785419258237,"version":"3.56.0"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,8,8]],"date-time":"2015-08-08T00:00:00Z","timestamp":1438992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The efficacy of sacral nerve stimulation (<jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content>) in low anterior resection syndrome (<jats:styled-content style=\"fixed-case\">LARS<\/jats:styled-content>) is largely undocumented. A review of the literature was carried out to study this question.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Pubmed, Medline and Cochrane databases were searched for relevant articles up to August 2014. Studies were included if they evaluated the use of<jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content>following rectal resection and assessed at least one of the following end\u2010points: bowel function, quality of life and ano\u2010neorectal physiology. No restrictions on language or study size were made.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven papers were identified including one case report and six prospective case series. These included 43 patients with a median follow\u2010up of 15\u00a0months. After peripheral nerve evaluation definitive implantation was carried out in 34 (79.1%) patients. Overall, 32 (94.1%) of the 34 patients experienced improvement of symptoms which, based on intention to treat, was 32\/43 (74.4%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The review suggests that<jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content>for faecal incontinence in<jats:styled-content style=\"fixed-case\">LARS<\/jats:styled-content>has success rates comparable to its use for other forms of faecal incontinence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12968","type":"journal-article","created":{"date-parts":[[2015,4,4]],"date-time":"2015-04-04T07:38:18Z","timestamp":1428133098000},"page":"762-771","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["A systematic review of sacral nerve stimulation for low anterior resection syndrome"],"prefix":"10.1111","volume":"17","author":[{"given":"L.","family":"Ramage","sequence":"first","affiliation":[{"name":"Department 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