{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:18Z","timestamp":1787014038232,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,11,7]],"date-time":"2015-11-07T00:00:00Z","timestamp":1446854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      Conventional laparoscopic surgery for rectal cancer management is now widely accepted as an alternative to open surgery, bestowing specific advantages without causing detriment to oncological outcome. Evolving from this, single\u2010incision laparoscopic surgery (\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      ) has been successfully utilized for the removal of colonic tumours, but the literature lacks data analysing the suitability of\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      for rectal cancer resection, particularly on oncological outcome. We report the medium\u2010term oncological outcome from a prospective observational study of\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      for rectal cancer, including high and low anterior resections.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A prospective electronic database was collated of all patients undergoing\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      rectal cancer resection in our institution, between 2009 and 2014. In addition to patient, tumour and operative data, histopathological and medium\u2010term oncological end\u2010points were recorded. Kaplan\u2013Meier curves were used to analyse survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010one patients underwent\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      for rectal cancer by high anterior resection (\n                      <jats:italic>n\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      34), low anterior resection with total mesorectal excision (\n                      <jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content>\n                      ) (\n                      <jats:italic>n\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      24) and low anterior resection with\n                      <jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content>\n                      and hand\u2010sewn colo\u2010anal anastomosis (\n                      <jats:italic>n\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      3). The median operation time was 105 (37\u2013280) min and 92% of cases were completed by\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      . The mean interval to resuming oral feeding was 11\u00a0h and the median length of stay was 2 (1\u20138) days. The median number of lymph nodes found by the histopathologist in the resected specimen was 18 (6\u201344) and all operations completely removed the tumour (R0 resection). At a median follow\u2010up of 46 (16\u201364) months, eight (13%) patients developed metastatic disease, of whom three had local recurrence. Overall, three patients have died, of whom all had metastatic disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Anterior resection with\n                      <jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content>\n                      for rectal cancer can be safely performed using the\n                      <jats:styled-content style=\"fixed-case\">SILS<\/jats:styled-content>\n                      technique, with acceptable histopathological results and good oncological outcome.\n                    <\/jats:p>\n                  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