{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T06:22:47Z","timestamp":1776493367143,"version":"3.51.2"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,2]],"date-time":"2016-02-02T00:00:00Z","timestamp":1454371200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to determine the clinical outcome of salvage surgery without restoring continuity for symptomatic chronic presacral sinus after low anterior resection (<jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content>) for rectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Out of a prospective cohort of 46 patients with chronic presacral sinus (&gt;\u00a01\u00a0year after <jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content>), 27 underwent completion proctectomy with omentoplasty between January 2005 and July 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The initial treatment for rectal cancer included neoadjuvant radiotherapy in 26 (96%) patients. Besides a chronic presacral sinus, a secondary fistula was present in 15 (56%) patients. Definitive salvage surgery was performed after a median of 40 (12\u2013350) months from the primary resection. The median hospital stay after single\u2010 and multiple\u2010stage salvage surgery was 11 and 17\u00a0days. Postoperative complications occurred in 44% of patients. The re\u2010intervention rate was 33% with a range of 1\u201310 interventions per patient. During a median follow\u2010up of 20 (4\u201345) months from salvage surgery, healing of the chronic presacral sinus occurred in 78% of patients, with a healing rate after single\u2010 and multiple\u2010stage procedures of 88% and 64% respectively (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.19).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with a symptomatic chronic presacral sinus after <jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content> for rectal cancer, in whom restoration of continuity is not intended, can be effectively managed by completion proctectomy with complete debridement of the sinus and fistula tracts followed by an omentoplasty to fill the presacral cavity, preferably as a single\u2010stage procedure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13086","type":"journal-article","created":{"date-parts":[[2015,8,16]],"date-time":"2015-08-16T10:01:46Z","timestamp":1439719306000},"page":"147-154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Intersphincteric completion proctectomy with omentoplasty for chronic presacral sinus after low anterior resection for rectal cancer"],"prefix":"10.1111","volume":"18","author":[{"given":"G. D.","family":"Musters","sequence":"first","affiliation":[{"name":"Department of Surgery Academic Medical Centre University of Amsterdam Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. A.","family":"Borstlap","sequence":"additional","affiliation":[{"name":"Department of Surgery Academic Medical Centre University of Amsterdam Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. A.","family":"Bemelman","sequence":"additional","affiliation":[{"name":"Department of Surgery Academic Medical Centre University of Amsterdam Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. J.","family":"Buskens","sequence":"additional","affiliation":[{"name":"Department of Surgery Academic Medical Centre University of Amsterdam Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. J.","family":"Tanis","sequence":"additional","affiliation":[{"name":"Department of Surgery Academic Medical Centre University of Amsterdam Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6594"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-013-2381-4"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01585.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02377.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-014-1967-y"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(07)70047-5"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-013-2193-4"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000040"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12094"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-014-1163-7"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01858.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(01)00378-4"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/110241599750006956"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1001\/jama.1984.03350150034017","article-title":"Lipid angiogenic factor from omentum","volume":"252","author":"Goldsmith HS","year":"1984","journal-title":"JAMA"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02087559"},{"key":"e_1_2_8_17_1","first-page":"222","article-title":"The greater omentum as a site of antibody synthesis","volume":"42","author":"Walker FC","year":"1961","journal-title":"Br J Exp Pathol"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-003-0040-7"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-010-0600-5"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.13086","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.13086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T14:21:15Z","timestamp":1696342875000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.13086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/codi.13086"],"URL":"https:\/\/doi.org\/10.1111\/codi.13086","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"2015-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-05-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-02-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}