{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:16:16Z","timestamp":1789193776382,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:00:00Z","timestamp":1451865600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,1]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>In paediatric and adult patients with neurogenic bowel, transanal irrigation (TAI<\/jats:styled-content>) of the colon has gained popularity due to the introduction of a specifically designed device. The aim of this pilot study was to present the results of TAI<\/jats:styled-content> using the Peristeen\u00ae<\/jats:sup> TAI<\/jats:styled-content> system in a group of paediatric patients with anorectal malformation (ARM<\/jats:styled-content>) and congenital or acquired spinal cord lesions (SCL<\/jats:styled-content>s).<\/jats:p><\/jats:sec>Method<\/jats:title>Eight Italian paediatric surgery and spina bifida centres participated in the study. The inclusion criteria were age between 6 and 17\u00a0years, weight above 20\u00a0kg and unsatisfactory bowel management. Patients with chronic inflammatory bowel disease, mental disability and surgery within the previous 3\u00a0months were excluded. At the beginning of treatment (T0) and after 3\u00a0months (T1) the Bristol scale, a questionnaire assessing bowel function, and two questionnaires on quality of life (QoL) for patients aged 6\u201311\u00a0years (CHQ<\/jats:styled-content>\u2010pf50) and 12\u201317\u00a0years (SF<\/jats:styled-content>36) were administered.<\/jats:p><\/jats:sec>Results<\/jats:title>Eighty\u2010three patients were enrolled, and seventy\u2010eight completed the study (41 ARM<\/jats:styled-content>s, 37 SCL<\/jats:styled-content>s). At T1, constipation was reduced in ARM<\/jats:styled-content>s from 69% to 25.6% and in SCL<\/jats:styled-content>s from 92.7% to 41.5%, faecal incontinence in ARM<\/jats:styled-content>s from 50% to 18.6% and in SCL<\/jats:styled-content>s from 39% to 9.8% and flatus incontinence in ARM<\/jats:styled-content>s from 20.9% to 9.8% and in SCL<\/jats:styled-content>s from 31.7% to 10%. At T0, the Bristol Stool Scale types were 1\u20132 in 45% of ARM<\/jats:styled-content>s and 77.5% of SCL<\/jats:styled-content> patients, whereas at T1 types 1\u20132 were recorded in only 2.5% of SCL<\/jats:styled-content> patients. QoL improved in both groups. In the younger group, a significant improvement in QoL was recorded in ARM<\/jats:styled-content> patients for eight of nine variables and in SCL<\/jats:styled-content> patients for seven of nine variables.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This study showed that Peristeen TAI<\/jats:styled-content> resulted in a significant time reduction in colonic cleansing, increased independence from the carer and improved QoL in paediatric patients with ARM<\/jats:styled-content>s and SCL<\/jats:styled-content>s.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13101","type":"journal-article","created":{"date-parts":[[2015,8,25]],"date-time":"2015-08-25T08:19:31Z","timestamp":1440490771000},"page":"86-93","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Peristeen\u00ae<\/sup> transanal irrigation in paediatric patients with anorectal malformations and spinal cord lesions: a multicentre Italian study"],"prefix":"10.1111","volume":"18","author":[{"given":"P.","family":"Midrio","sequence":"first","affiliation":[{"name":"Pediatric Surgery Unit Department of Woman and Child Health University Hospital Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2282-8207","authenticated-orcid":false,"given":"G.","family":"Mosiello","sequence":"additional","affiliation":[{"name":"Neuro\u2010Urology Unit\/Spina Bifida Center and Department of Medical and Surgical Neonatology Bambino Ges\u00f9 Children Hospital and Research Institute Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ausili","sequence":"additional","affiliation":[{"name":"Spina Bifida Center Department of Paediatric Science Catholic University Medical School Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Gamba","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit Department of Woman and Child Health University Hospital Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Marte","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit Second University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Lombardi","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit Pediatric Hospital Parma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. D.","family":"Iacobelli","sequence":"additional","affiliation":[{"name":"Neuro\u2010Urology Unit\/Spina Bifida Center and Department of Medical and Surgical Neonatology Bambino Ges\u00f9 Children Hospital and Research Institute Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Caponcelli","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit Vittore Buzzi Pediatric Hospital Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Marrello","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit Annunziata Hospital Cosenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Meroni","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit Vittore Buzzi Pediatric Hospital Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Brisighelli","sequence":"additional","affiliation":[{"name":"Department of 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