{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:52:07Z","timestamp":1792428727500,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,11,7]],"date-time":"2015-11-07T00:00:00Z","timestamp":1446854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Industry-Academia-Research major project of the Guangzhou Science and Technology Program","award":["2060404"],"award-info":[{"award-number":["2060404"]}]},{"name":"Science and Technology Planning Project of Guangdong Province, China","award":["2014A020211009"],"award-info":[{"award-number":["2014A020211009"]}]},{"name":"Natural Science Foundation of Guangdong Province, China","award":["2015A030313063"],"award-info":[{"award-number":["2015A030313063"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study assessed the effect of intra\u2010operative electrical nerve stimulation (<jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content>) on pelvic autonomic nerve preservation (<jats:styled-content style=\"fixed-case\">PANP<\/jats:styled-content>) during laparoscopic resection for rectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A total of 189 consecutive cases of radical laparoscopic proctectomy were included. <jats:styled-content style=\"fixed-case\">PANP<\/jats:styled-content> was assessed visually or with <jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content>. Urinary function was evaluated by residual urine volume (<jats:styled-content style=\"fixed-case\">RUV<\/jats:styled-content>), International Prostatic Symptom Score (<jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content>) and recatheterization rate. Erectile function was evaluated using the International Index of Erectile Function (<jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content>\u20105) scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content> successfully confirmed <jats:styled-content style=\"fixed-case\">PANP<\/jats:styled-content> in 65 (91.5%) patients, while direct vision confirmed <jats:styled-content style=\"fixed-case\">PANP<\/jats:styled-content> in only 72 (61.0%) patients. Compared with the successfully confirmed patients, failed patients in the <jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content> group exhibited higher postoperative <jats:styled-content style=\"fixed-case\">RUV<\/jats:styled-content> (100.0\u00a0\u00b1\u00a034.6 <jats:italic>vs<\/jats:italic> 25.2\u00a0\u00b1\u00a013.6\u00a0ml, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.003), higher <jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content> (7\u00a0days, 20.0\u00a0\u00b1\u00a08.6 <jats:italic>vs<\/jats:italic> 6.5\u00a0\u00b1\u00a02.4, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.012; 1\u00a0month, 13.5\u00a0\u00b1\u00a06.0 <jats:italic>vs<\/jats:italic> 5.3\u00a0\u00b1\u00a01.9, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.020; 6\u00a0months, 11.7\u00a0\u00b1\u00a05.1 <jats:italic>vs<\/jats:italic> 4.5\u00a0\u00b1\u00a01.7, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.018), a greater number of incidences of a micturition disorder (66.7% <jats:italic>vs<\/jats:italic> 1.5%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.000), higher recatheterization rates (33.3% <jats:italic>vs<\/jats:italic> 1.5%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.017) and a lower <jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content> score at 3\u00a0months (8.25\u00a0\u00b1\u00a00.96 <jats:italic>vs<\/jats:italic> 10.93\u00a0\u00b1\u00a01.99, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.012) and 6\u00a0months (12.50\u00a0\u00b1\u00a01.29 <jats:italic>vs<\/jats:italic> 15.63\u00a0\u00b1\u00a01.65, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.001) postoperatively. Compared with the vision group, the <jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content> group had less deterioration in postoperative <jats:styled-content style=\"fixed-case\">RUV<\/jats:styled-content> (31.5\u00a0\u00b1\u00a026.4 <jats:italic>vs<\/jats:italic> 54.0\u00a0\u00b1\u00a046.7\u00a0ml, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.000), lower <jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content> (7\u00a0days, 7.7\u00a0\u00b1\u00a05.0 <jats:italic>vs<\/jats:italic> 11.0\u00a0\u00b1\u00a06.6, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.000; 1\u00a0month, 6.0\u00a0\u00b1\u00a03.3 <jats:italic>vs<\/jats:italic> 7.6\u00a0\u00b1\u00a05.4, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.012) and higher <jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content> score (3\u00a0months, 10.69\u00a0\u00b1\u00a02.07 <jats:italic>vs<\/jats:italic> 9.42\u00a0\u00b1\u00a02.05, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.001; 6\u00a0months, 15.36\u00a0\u00b1\u00a01.85 <jats:italic>vs<\/jats:italic> 13.64\u00a0\u00b1\u00a02.00, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.000) as well as a lower incidence of urination disorders (7.0% <jats:italic>vs<\/jats:italic> 17.8%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.038).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content> is effective for the accurate evaluation of <jats:styled-content style=\"fixed-case\">PANP<\/jats:styled-content> during radical laparoscopic proctectomy. Combined with <jats:styled-content style=\"fixed-case\">INS<\/jats:styled-content>, laparoscopic proctectomy is more effective in urogenital function protection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13115","type":"journal-article","created":{"date-parts":[[2015,9,12]],"date-time":"2015-09-12T09:46:47Z","timestamp":1442051207000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of intra\u2010operative autonomic nerve stimulation on pelvic nerve preservation during radical laparoscopic proctectomy"],"prefix":"10.1111","volume":"17","author":[{"given":"J.\u2010F.","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery Third Affiliated Hospital of Sun Yat\u2010sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery 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