{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:36:53Z","timestamp":1760985413881},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:00:00Z","timestamp":1451865600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Low anterior resection (<jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content>) can present a formidable surgical challenge, particularly for tumours located in the distal third of the rectum. Transanal total mesorectal excision (ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content>) aims to overcome some of these difficulties. We report our initial experience with this technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>From June 2013 to September 2014, 20 selected patients underwent transanal rectal resection for various malignant and benign low rectal pathologies. All patients with rectal cancer were discussed at a multidisciplinary team meeting. Data were entered into a prospective managed international database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 20 patients (14 male), seventeen (85%) had rectal cancer lying at a median distance of 2\u00a0cm (range 0\u20137) from the anorectal junction. The operations performed included <jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content> (16). Abdominoperineal excision (2) and completion proctectomy (2), all of which were performed by a minimally invasive approach with three conversions. The mean operation time was 315.3\u00a0min. There were six postoperative complications of which two (10%) were Clavien\u2013Dindo Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>b (pelvic haematoma and a late contained anastomotic leakage). The median length of stay was 7\u00a0days. The <jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> specimen was intact in 94.1% of cancer cases. The mean number of harvested lymph nodes was 23.2. There was only one positive circumferential resection margin (tumour deposit; R1 rate 5.9%). One patient developed a distant recurrence (median follow\u2010up 10\u00a0months, range 6\u201321).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> was safe in this small series of patients. It is especially attractive in patients with a narrow and irradiated pelvis and a tumour in the lower third of the rectum. Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> is technically demanding, but the good outcomes should prompt randomized studies and prospective registration of all ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> cases in an international registry.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13227","type":"journal-article","created":{"date-parts":[[2015,12,8]],"date-time":"2015-12-08T17:58:04Z","timestamp":1449597484000},"page":"45-50","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Transanal rectal resection: an initial experience of 20 cases"],"prefix":"10.1111","volume":"18","author":[{"given":"N. C.","family":"Buchs","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Churchill Hospital University Hospitals of Oxford Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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