{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T08:47:16Z","timestamp":1782982036932,"version":"3.54.5"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,6,8]],"date-time":"2016-06-08T00:00:00Z","timestamp":1465344000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Minimally invasive approaches to proctectomy for rectal cancer have not been widely adopted due to inherent technical challenges. A modification of traditional transabdominal mobilization, termed transanal total mesorectal excision (Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content>), has the potential to improve access to the distal rectum. The aim of the current study is to assess outcomes following Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> for rectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This is a retrospective analysis of a prospectively maintained database of consecutive patients who underwent Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> for rectal cancer at a single institution. The study period was from 1 March 2012 to 31 July 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period 50 patients underwent Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content>. The median tumour distance from the anal verge was 4.4 (3.0\u20135.5)\u00a0cm. The rate of conversion from a planned minimally invasive approach was 2.2%. The median operative time was 267.0 (227.0\u2013331.0)\u00a0min. The median lymph node yield was 18.0 (12.0\u201323.8), the macroscopic quality assessment of the resected specimen was incomplete in 2% and the circumferential resection margin positivity rate was 4%. Intra\u2010operative morbidity occurred in 6% and the 30\u00a0day morbidity rate was 36%. The median length of stay was 4.5 (4.0\u20138.0)\u00a0days. The median follow\u2010up was 15.1 (7.0\u201323.2) months; two patients have developed a local recurrence and eight patients have developed distant recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These data suggest that Ta<jats:styled-content style=\"fixed-case\">TME<\/jats:styled-content> for rectal cancer is feasible with an acceptable pathological outcome and morbidity profile. Further data on functional and long\u2010term survival outcomes are required.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13263","type":"journal-article","created":{"date-parts":[[2016,1,10]],"date-time":"2016-01-10T11:16:10Z","timestamp":1452424570000},"page":"570-577","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":87,"title":["Transanal total mesorectal excision for rectal cancer: early outcomes in 50 consecutive patients"],"prefix":"10.1111","volume":"18","author":[{"given":"J. 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