{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:30:21Z","timestamp":1789655421750,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T00:00:00Z","timestamp":1467590400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Novel minimally invasive techniques aimed to reposition the haemorrhoidal zone have been established for prolapsing haemorrhoids. We present a prospective randomized controlled trial to evaluate the efficacy of additional Doppler\u2010guided ligation of submucosal haemorrhoidal arteries (<jats:styled-content style=\"fixed-case\">DG<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HAL<\/jats:styled-content>) in patients with symptomatic Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> haemorrhoids. The trial was registered as ClinicalTrials.gov identifier <jats:styled-content style=\"fixed-case\">NCT<\/jats:styled-content>02372981.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>All consecutive patients with symptomatic Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> haemorrhoids were randomly allocated to one of the two study arms: (i) Group A, <jats:styled-content style=\"fixed-case\">DG<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HAL<\/jats:styled-content> with mucopexy or (ii) Group B, mucopexy alone. End\u2010points were postoperative pain, faecal incontinence, bleeding, residual prolapse and alterations of the vascularization of the anorectal vascular plexus. Vascularization of the anorectal vascular plexus was assessed by transperineal contrast enhanced ultrasound. Patients recorded their symptoms in a diary maintained for a month.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty patients were recruited and randomized to the two study groups. Patients in Group A had less pain in the first two postoperative weeks. At the 12\u2010month follow\u2010up, two patients in Group A (10%) and one in Group B (5%) showed recurrent Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> haemorrhoids (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.274). No significant morphological changes were observed in the transperineal ultrasound findings between the preoperative assessment and the assessment at 1 and 6\u00a0months in either group (<jats:italic>P\u00a0<\/jats:italic>&gt;<jats:italic>\u00a0<\/jats:italic>0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Mucopexy techniques for treating prolapsing haemorrhoids are effective, but <jats:styled-content style=\"fixed-case\">DG<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HAL<\/jats:styled-content> does not add significantly to the results achieved by mucopexy. Repositioning the haemorrhoidal zone is the key to success, and mucopexy should be placed at the sites of the largest visible prolapse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13280","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T02:00:46Z","timestamp":1453255246000},"page":"710-716","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Doppler\u2010guided haemorrhoidal artery ligation with suture mucopexy compared with suture mucopexy alone for the treatment of Grade <scp>III<\/scp> haemorrhoids: a prospective randomized controlled trial"],"prefix":"10.1111","volume":"18","author":[{"given":"F.","family":"Aigner","sequence":"first","affiliation":[{"name":"Department for General, Visceral and Transplantation Surgery Charit\u00e9 Universit\u00e4tsmedizin Berlin Germany"},{"name":"Department of Visceral, Transplant and Thoracic Surgery Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Kronberger","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Oberwalder","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Loizides","sequence":"additional","affiliation":[{"name":"Department of Radiology Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Ulmer","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics, Informatics and Health Economics Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Gruber","sequence":"additional","affiliation":[{"name":"Department of Radiology Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Pratschke","sequence":"additional","affiliation":[{"name":"Department for General, Visceral and Transplantation Surgery Charit\u00e9 Universit\u00e4tsmedizin Berlin Germany"},{"name":"Department of Visceral, Transplant and Thoracic Surgery Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Peer","sequence":"additional","affiliation":[{"name":"Department of Radiology Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Gruber","sequence":"additional","affiliation":[{"name":"Department of Radiology Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810707"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0572-3"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01729.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7700"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12024"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181af50f4"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2002.11.003"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-011-0780-7"},{"key":"e_1_2_8_10_1","first-page":"151","article-title":"Transanal doppler\u2010guided hemorrhoidal artery ligation\/recto anal repair (HAL\u2010RAR) for treatment of Grade 3\u20134 hemorrhoids: a new mini\u2010invasive technology","volume":"27","author":"Zagriadski\u0131\u02c7 EA","year":"2008","journal-title":"Pelviperineology"},{"key":"e_1_2_8_11_1","first-page":"37","article-title":"Recto Anal Repair (RAR): a viable new treatment option for high\u2010grade hemorrhoids. 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