{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T20:40:44Z","timestamp":1774039244053,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T00:00:00Z","timestamp":1470096000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study used a national registry to compare the outcome after a low Hartmann's procedure (<jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content>), defined as removal of most of the rectum to leave a short anorectal stump and an end colostomy, and low anterior resection (LA) with or without a diverting ileostomy (<jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content>) in rectal cancer patients all of whom had received preoperative neoadjuvant radiotherapy (<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Patients who underwent <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with or without <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content> for rectal cancer after <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content> between 2009 and 2013 were identified from the Dutch Surgical Colorectal Audit. The postoperative outcome was compared between the three groups and risk of complications, reoperation and mortality were analysed in a multivariable model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 4288 patients were included, of whom 27.8% underwent <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content>, 20.2% <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> and 52.0% <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content>. Thirty\u2010day mortality was higher after <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> (3.2% <jats:italic>vs<\/jats:italic> 1.3% and 1.3% for <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with or without <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content>,<jats:italic> P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), but <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> was not an independent predictor of mortality in multivariable analysis. <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content> were associated with a lower rate of abdominal infective complications (6.5% and 10.1% <jats:italic>vs<\/jats:italic> 16.2%, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001) and reoperation (7.3% and 8.1% <jats:italic>vs<\/jats:italic> 16.5%, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). In multivariable analysis, <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.35, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.26\u20130.47) and <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.43, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.33\u20130.54) were associated with a lower risk of reoperation than <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> alone. <jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> was associated with a lower risk of any postoperative complication than <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with or without <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.81, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.66\u20130.98).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LHP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content> were associated with fewer infective complications and reoperations than <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> alone. The rate of any complication was less after <jats:styled-content style=\"fixed-case\">LHR<\/jats:styled-content> than <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> with or without <jats:styled-content style=\"fixed-case\">DI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13281","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T15:44:47Z","timestamp":1453304687000},"page":"785-792","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Comparison of a low Hartmann's procedure with low colorectal anastomosis with and without defunctioning ileostomy after radiotherapy for rectal cancer: results from a national registry"],"prefix":"10.1111","volume":"18","author":[{"given":"F. H. 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