{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:14:58Z","timestamp":1769602498023,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T00:00:00Z","timestamp":1470096000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The optimal extent of mesenteric resection in colon cancer surgery is not known. We have previously shown an increased mortality associated with wider mesenteric resection in right hemicolectomy. This study compares the short\u2010 and long\u2010term outcome in three variations of right hemicolectomy based on the position of the vascular ligature in the mesentery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In all, 2084 cases of cancer in the caecum or ascending colon were identified in the Swedish Colorectal Cancer Registry and categorized according to the position of the vascular ligature: central ligation of ileocolic vessels (ICVs)\u00a0\u00b1\u00a0right colic vessels (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>390), central ligation of ICVs + right branch of middle colic vessels (MCVs) (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1360) and central ligation of ICVs\u00a0+\u00a0central ligation of MCVs (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>334).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Neither 3\u2010year overall survival, 3\u2010year disease\u2010free survival nor local recurrence rate differed between the groups (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.604; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.247; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.237). There was still no difference after multivariate analysis adjusted for age, sex, American Society of Anesthesiologists classification, TNM stage and adjuvant therapy. An increased peri\u2010operative mortality, however, was observed in extended mesenteric resections, increasing from 0.8% in non\u2010extended to 3.6% in more extended resection, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.025.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study showed no survival benefit by more extended mesenteric resection, indicating that there is no need to extend the mesenteric resection to involve the MCVs in cancer of the caecum or ascending colon. On the contrary, increased peri\u2010operative mortality by more extensive mesenteric resection was noted suggesting that a more conservative approach may be favourable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13305","type":"journal-article","created":{"date-parts":[[2016,2,20]],"date-time":"2016-02-20T21:07:04Z","timestamp":1456002424000},"page":"773-778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["No benefit of extended mesenteric resection with central vascular ligation in right\u2010sided colon cancer"],"prefix":"10.1111","volume":"18","author":[{"given":"F.","family":"Olofsson","sequence":"first","affiliation":[{"name":"Department of Surgery Sk\u00e5ne University Hospital, Malm\u00f6 Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Buchwald","sequence":"additional","affiliation":[{"name":"Department of Surgery Helsingborg Hospital Lund 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