{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T15:23:50Z","timestamp":1783783430796,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of this study was to assess the efficacy of percutaneous nerve evaluation (<jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content>) in women with faecal incontinence (<jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content>) following obstetric anal sphincter injury and to relate the outcomes to baseline factors, with special emphasis on the extent of the sphincter defect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a prospective study at a tertiary colorectal referral unit at the University Hospital of North Norway conducted from 2012 to 2014. Sixty\u2010three women underwent a 3\u2010week <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> using a tined lead and the Verify<jats:sup>\u00ae<\/jats:sup> external neurostimulator. The primary outcome was efficacy, defined as the percentage reduction in weekly <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content> episodes, and patients with a reduction of 50% or more were defined as responders. Baseline factors affecting the primary outcome were explored. Sphincter defects were classified with a validated three\u2010dimensional endoanal ultrasound defect score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010six (89%) of the 63 women were responders with a reduction in weekly <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content> episodes of 94.5%, from a median (interquartile range) of 4.8 (2.0\u201311.0) to 0.5 (0\u20132.0) (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). Twenty\u2010nine (52%) reported no weekly <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content> episodes, and urgency episodes disappeared in 18 (32%). In the multivariable linear regression model, efficacy was related to concomitant urinary incontinence (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.04), body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.03) and pain during <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.046) but not to the extent of the sphincter defect (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.1). Responders had a higher St Mark's score than nonresponders (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.046).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The vast majority of women had successful <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> tests. Responders had higher baseline St Mark's scores than nonresponders. Efficacy was related to concomitant urinary incontinence, <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and pain, not to the extent of the sphincter defect.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13472","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T14:23:18Z","timestamp":1469629398000},"page":"274-282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Sacral neuromodulation for faecal incontinence following obstetric sphincter injury \u2013 outcome of percutaneous nerve evaluation"],"prefix":"10.1111","volume":"19","author":[{"given":"M. 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O.","family":"Lindsetmo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery University Hospital of North Norway Tromsoe Norway"},{"name":"Institute of Clinical Medicine The Arctic University of Norway Tromsoe Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kumle","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospital of North Norway Tromsoe Norway"},{"name":"Narvik University College Narvik Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Stedenfeldt","sequence":"additional","affiliation":[{"name":"National Advisory Board of Continence and Pelvic Floor Health of Norway University Hospital of North Norway Tromsoe Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Norderval","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery University Hospital of North Norway 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