{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T05:06:06Z","timestamp":1769922366212,"version":"3.49.0"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T00:00:00Z","timestamp":1493856000000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Sphincteroplasty (<jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>) is used to treat faecal incontinence (<jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content>) in patients with a sphincter defect. Although sacral nerve stimulation (<jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content>) is used in patients, its outcome in patients with a sphincter defect has not been definitively evaluated. We compared the results of <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content> associated with a sphincter defect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Patients treated by <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content> with an associated sphincter defect were retrospectively identified from an Institutional Review Board approved prospective database. Patients with ultrasound evidence of a sphincter defect were matched by age, gender and body mass index. The main outcome measure was change in the Cleveland Clinic Florida Faecal Incontinence Score (<jats:styled-content style=\"fixed-case\">CCF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FIS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010six female patients with a sphincter defect were included in the study. The 13 patients in each group were similar for age, body mass index, initial <jats:styled-content style=\"fixed-case\">CCF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FIS<\/jats:styled-content> and the duration of follow\u2010up. No differences were observed in parity (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1.00), the rate of concomitant urinary incontinence (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.62) or early postoperative complications. Within\u2010group analysis showed a significant reduction of the <jats:styled-content style=\"fixed-case\">CCF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FIS<\/jats:styled-content> among patients having <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> (15.9\u20138.4; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.003) but not SP (16.9\u201312.9; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.078). There was a trend towards a more significant improvement in <jats:styled-content style=\"fixed-case\">CCF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FIS<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content> than in the <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content> group (post\u2010treatment <jats:styled-content style=\"fixed-case\">CCF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FIS<\/jats:styled-content> 8.4 <jats:italic>vs<\/jats:italic> 12.9, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.06). Net improvement in <jats:styled-content style=\"fixed-case\">CCF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FIS<\/jats:styled-content> was not significantly different between the groups (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.06).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Significant improvement in CCF\u2010FIS was observed in patients treated with SNS but not SP patients. A trend towards better results was seen with <jats:styled-content style=\"fixed-case\">SNS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13510","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T04:03:34Z","timestamp":1473739414000},"page":"456-461","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Faecal incontinence in patients with a sphincter defect: comparison of sphincteroplasty and sacral nerve stimulation"],"prefix":"10.1111","volume":"19","author":[{"given":"F. G.","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Cleveland Clinic Florida Weston Florida USA"},{"name":"National Council for Scientific and Technological Development (CNPq) Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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