{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:22:29Z","timestamp":1788416549401,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T00:00:00Z","timestamp":1499299200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      Advances in laparoscopic techniques combined with enhanced recovery pathways have led to faster recuperation and discharge after colorectal surgery. Peripheral nerve blockade using transversus abdominis plane (\n                      <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content>\n                      ) blocks reduce opioid requirements and provide better analgesia for laparoscopic colectomies than do inactive controls. This double\u2010blind randomized study was performed to compare\n                      <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content>\n                      blocks using bupivacaine with standardized wound infiltration with local anaesthetic (\n                      <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010one patients were randomized to receive either\n                      <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content>\n                      block or wound infiltration. The\n                      <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content>\n                      blocks were performed by experienced anaesthetists who used ultrasound guidance to deliver 40\u00a0ml of 0.25% bupivacaine post\u2010induction into the transverse abdominis plane. In the control group, 40\u00a0ml of 0.25% bupivacaine was injected around the trocar and the extraction site by the surgeon. Both groups received patient\u2010controlled analgesia (\n                      <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content>\n                      ) with intravenous morphine. Patients and nursing staff assessed pain scores 6, 12, 24 and 48\u00a0h after surgery. The primary outcome was overall morphine use in the first 48\u00a0h.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 71 patients, 20 underwent a right hemicolectomy and 51 a high anterior resection. The modified intention\u2010to\u2010treat analysis showed no significant differences in overall morphine use [47.3 (36.2\u201358.5) mg\n                      <jats:italic>vs<\/jats:italic>\n                      46.7 (36.2\u201357.3) mg; mean (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ),\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      0.8663] in the first 48\u00a0h. Pain scores were similar at 6, 12, 24 and 48\u00a0h. No differences were found regarding time to mobilization, resumption of diet and length of hospital stay.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      In elective laparoscopic colectomies, standardized wound infiltration with\n                      <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\n                      has the same analgesic effect as\n                      <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content>\n                      blocks post\u2010induction using bupivacaine at 48\u00a0h.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.13578","type":"journal-article","created":{"date-parts":[[2016,12,10]],"date-time":"2016-12-10T09:03:49Z","timestamp":1481360629000},"page":"681-689","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["No benefit of ultrasound\u2010guided transversus abdominis plane blocks over wound infiltration with local anaesthetic in elective laparoscopic colonic surgery: results of a double\u2010blind randomized controlled trial"],"prefix":"10.1111","volume":"19","author":[{"given":"A.","family":"Rashid","sequence":"first","affiliation":[{"name":"Nuffield Department of Anaesthetics Oxford University Hospitals NHS Foundation Trust Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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