{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:41:26Z","timestamp":1779115286293,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T00:00:00Z","timestamp":1506988800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Sacral nerve stimulation has become a preferred method for the treatment of faecal incontinence in patients who fail conservative (non\u2010operative) therapy. In previous small studies, sacral nerve stimulation has demonstrated improvement of faecal incontinence and quality of life in a majority of patients with low anterior resection syndrome. We evaluated the efficacy of sacral nerve stimulation in the treatment of low anterior resection syndrome using a recently developed and validated low anterior resection syndrome instrument to quantify symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective review of consecutive patients undergoing sacral nerve stimulation for the treatment of low anterior resection syndrome was performed. Procedures took place in the Division of Colon and Rectal Surgery at two academic tertiary medical centres. Pre\u2010 and post\u2010treatment Cleveland Clinic Incontinence Scores and Low Anterior Resection Syndrome scores were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve patients (50% men) suffering from low anterior resection syndrome with a mean age of 67.8 (\u00b110.8) years underwent sacral nerve test stimulation. Ten patients (83%) proceeded to permanent implantation. Median time from anterior resection to stimulator implant was 16 (range 5\u2013108) months. At a median follow\u2010up of 19.5 (range 4\u201342) months, there were significant improvements in Cleveland Clinic Incontinence Scores and Low Anterior Resection Syndrome scores (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sacral nerve stimulation improved symptoms in patients suffering from low anterior resection syndrome and may therefore be a viable treatment option.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13701","type":"journal-article","created":{"date-parts":[[2017,5,6]],"date-time":"2017-05-06T13:54:37Z","timestamp":1494078877000},"page":"927-933","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Sacral nerve stimulation can be an effective treatment for low anterior resection syndrome"],"prefix":"10.1111","volume":"19","author":[{"given":"S. M.","family":"Eftaiha","sequence":"first","affiliation":[{"name":"Division of Colon and Rectal Surgery University of Illinois Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Balachandran","sequence":"additional","affiliation":[{"name":"Chicago Medical School Rosalind Franklin University of Medicine and Science North Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Marecik","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery University of Illinois Chicago Illinois USA"},{"name":"Chicago Medical School Rosalind Franklin University of Medicine and Science North Chicago Illinois USA"},{"name":"Division of Colon and Rectal Surgery Advocate Lutheran General Hospital Park Ridge Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mellgren","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery University of Illinois Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Nordenstam","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery University of Illinois Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Melich","sequence":"additional","affiliation":[{"name":"Department of General Surgery Royal Columbian Hospital University of British Columbia New Westminster BC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. M.","family":"Prasad","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery University of Illinois Chicago Illinois USA"},{"name":"Division of Colon and Rectal Surgery Advocate Lutheran General Hospital Park Ridge Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. J.","family":"Park","sequence":"additional","affiliation":[{"name":"Chicago Medical School Rosalind Franklin University of Medicine and Science North Chicago Illinois USA"},{"name":"Division of Colon and Rectal Surgery Advocate Lutheran General Hospital Park Ridge Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182758c2b"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182214f11"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003840050042"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70236-X"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235256"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0007-1323.2001.01937.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0049-1"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9223"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12968"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31824f1c21"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02517.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12952"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0884-5"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.02066.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-012-0823-8"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1687-8"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-004-0729-7"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0412-9"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-008-0485-z"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000116"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02055598"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181ca74b4"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0919-y"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2014.01.003"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.13701","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.13701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:56:13Z","timestamp":1695556573000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.13701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/codi.13701"],"URL":"https:\/\/doi.org\/10.1111\/codi.13701","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"2016-09-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-02-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}