{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T01:55:25Z","timestamp":1788486925944,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T00:00:00Z","timestamp":1506988800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2017,10]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>The operative treatment for non\u2010metastatic appendiceal carcinoma is controversial despite the recommendation of right hemicolectomy (RH<\/jats:styled-content>) by many researchers. The aim of this population\u2010based study was to compare outcomes after RH<\/jats:styled-content> and less radical resection than right hemicolectomy (LRH<\/jats:styled-content>).<\/jats:p><\/jats:sec>Method<\/jats:title>A total of 1144 patients who underwent resection with additional lymphadenectomy of Stages I\u2013III<\/jats:styled-content> appendiceal carcinoma from 2004 to 2012 were identified in the Surveillance, Epidemiology and End Results database. Overall survival (OS<\/jats:styled-content>) and cancer\u2010specific survival (CSS<\/jats:styled-content>) after RH<\/jats:styled-content> and LRH<\/jats:styled-content> were assessed by unadjusted and risk\u2010adjusted Cox regression analysis and by propensity score matched analysis.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 855 (74.7%) patients underwent RH<\/jats:styled-content> and 289 (25.3%) underwent LRH<\/jats:styled-content>. In an unadjusted analysis, survival after LRH<\/jats:styled-content> and RH<\/jats:styled-content> did not differ in OS<\/jats:styled-content> [hazard ratio (HR<\/jats:styled-content>) 0.95, 95% CI<\/jats:styled-content> 0.71\u20131.26, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.707] and CSS<\/jats:styled-content> (HR<\/jats:styled-content> 0.95, 95% CI<\/jats:styled-content> 0.69\u20131.32, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.762). The 5\u2010year OS<\/jats:styled-content> and CSS<\/jats:styled-content> in patients who underwent RH<\/jats:styled-content> were 71.6% (95% CI<\/jats:styled-content> 67.8\u201375.6%) and 76.4% (95% CI<\/jats:styled-content> 72.8\u201380.3) compared with 73.8% (95% CI<\/jats:styled-content> 67.9\u201380.2) and 78.7% (95% CI<\/jats:styled-content> 73.2\u201384.7) in patients with LRH<\/jats:styled-content>, respectively. No relevant difference in survival between LRH<\/jats:styled-content> and RH<\/jats:styled-content> could be observed in a multivariable analysis (OS<\/jats:styled-content>, HR<\/jats:styled-content> 0.90, 95% CI<\/jats:styled-content> 0.65\u20131.25, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.493; CSS<\/jats:styled-content>, HR<\/jats:styled-content> 0.87, 95% CI<\/jats:styled-content> 0.60\u20131.26, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.420) and after propensity score adjusted analysis (OS<\/jats:styled-content>, HR<\/jats:styled-content> 0.87, 95% CI<\/jats:styled-content> 0.62\u20131.22, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.442; CSS<\/jats:styled-content>, HR<\/jats:styled-content> 0.97, 95% CI<\/jats:styled-content> 0.67\u20131.40, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.883).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>In this retrospective analysis, survival after RH<\/jats:styled-content> for non\u2010metastatic appendiceal carcinoma was not statistically significantly superior to LRH<\/jats:styled-content>. Hence, LRH<\/jats:styled-content> with lymphadenectomy might be sufficient for treatment of non\u2010metastatic appendiceal carcinoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13746","type":"journal-article","created":{"date-parts":[[2017,5,26]],"date-time":"2017-05-26T14:36:43Z","timestamp":1495809403000},"page":"895-906","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Survival after resection of appendiceal carcinoma by hemicolectomy and less radical than hemicolectomy: a\u00a0population\u2010based propensity score matched analysis"],"prefix":"10.1111","volume":"19","author":[{"given":"H.","family":"Elias","sequence":"first","affiliation":[{"name":"Department of Surgery Kantonsspital St Gallen St Gallen Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Galata","sequence":"additional","affiliation":[{"name":"Department of Surgery Universit\u00e4tsmedizin Mannheim Medical Faculty Mannheim University of Heidelberg Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Warschkow","sequence":"additional","affiliation":[{"name":"Department of Surgery Kantonsspital St Gallen St Gallen Switzerland"},{"name":"Institute of Medical Biometry and Informatics University of Heidelberg Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. 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