{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T08:12:07Z","timestamp":1780474327460,"version":"3.54.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T00:00:00Z","timestamp":1514937600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"medical research programme of the Health Authorities of North Norway","award":["6916\/SFP1049-12"],"award-info":[{"award-number":["6916\/SFP1049-12"]}]},{"name":"Medical Research Ethics, North Norway","award":["REK NORD 2011\/1300"],"award-info":[{"award-number":["REK NORD 2011\/1300"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to investigate the efficacy of sacral neuromodulation (<jats:styled-content style=\"fixed-case\">SNM<\/jats:styled-content>) in the treatment of faecal incontinence and concomitant urinary incontinence in women with a history of obstetric anal sphincter injury (<jats:styled-content style=\"fixed-case\">OASIS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In this prospective study, consecutive women with faecal incontinence following <jats:styled-content style=\"fixed-case\">OASIS<\/jats:styled-content> accepted for <jats:styled-content style=\"fixed-case\">SNM<\/jats:styled-content> were screened for concomitant urinary incontinence. The primary outcome was the change in urinary incontinence score on the International Consultation on Incontinence Questionnaire for Urinary Incontinence, Short Form (<jats:styled-content style=\"fixed-case\">ICIQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>), between baseline and 12\u00a0months. Secondary outcomes included the change in St Mark's score, sexual function and quality of life, change in grade of urinary incontinence and disappearance of urgency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From March 2012 to September 2014, 39 women with combined faecal incontinence and urinary incontinence received <jats:styled-content style=\"fixed-case\">SNM<\/jats:styled-content>. Thirty\u2010seven women were available for analysis after 12\u00a0months. The mean reduction in the <jats:styled-content style=\"fixed-case\">ICIQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content> score between the baseline and 12\u00a0months was 5.8 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 3.7\u20138.0, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). <jats:styled-content style=\"fixed-case\">ICIQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content> was reduced in 29 (78%) women, urinary incontinence resolved in 13\/37 (35%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 20%\u201350%) patients, and urgency disappeared in 14\/33 (42%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 26%\u201359%). The mean reduction in the St Mark's score was 10.6 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 8.6\u201312.7, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). Disease\u2010specific quality of life, Euroqual 5\u2010dimension visual analogue scale (<jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>) and several areas of sexual function changed significantly for the better.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>More than three\u2010quarters of the women with combined faecal and urinary incontinence following <jats:styled-content style=\"fixed-case\">OASIS<\/jats:styled-content> reported a successful outcome with reduction in <jats:styled-content style=\"fixed-case\">ICIQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content> at 12\u00a0months after <jats:styled-content style=\"fixed-case\">SNM<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13820","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T16:22:40Z","timestamp":1500567760000},"page":"59-67","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Sacral neuromodulation for combined faecal and urinary incontinence following obstetric anal sphincter injury"],"prefix":"10.1111","volume":"20","author":[{"given":"M. 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