{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T04:57:12Z","timestamp":1764046632181},"reference-count":56,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T00:00:00Z","timestamp":1504569600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Kom op tegen Kanker and Cancer Plan Belgium"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aims to describe the nature, incidence, severity and outcomes of in\u2010hospital postoperative complications (<jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s) in older patients undergoing elective surgery for colorectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Patients \u2265\u00a070 years old were identified from a prospectively collected database (2009\u20132015) focusing on the implementation of geriatric screening and assessment in patients with cancer. Medical and surgical <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s were retrieved retrospectively from the medical records, and the severity of the <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s was graded by the Clavien\u2013Dindo (<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>) grading system. The following outcomes were analysed comparing patients with and without <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> \u2265\u00a02 and <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> \u2265\u00a03 <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s: length of stay (<jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content>), transfer to the intensive care unit, 30\u2010day readmission rates, 30\u2010day and 1\u2010year mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the 190 patients included, medical <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s (40.5%) were more frequent than surgical <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s (17.9%), and 37.9% experienced <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> \u2265\u00a02 <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s. The most common medical <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s were infections (26.8%), transient confusion or altered mental function (12.1%), cardiac arrhythmia (4.7%), and ileus\/gastroparesis\/prolonged recovery of transit (4.7%). The most common surgical <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s were surgical site infections (12.1%), wound dehiscence\/bleeding (4.7%), anastomotic leak (3.7%) and surgical site bleeding (3.7%). The reoperation rate was 7.9%. <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> \u2265\u00a02 <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s led to 11 intensive care unit admissions and increased median postoperative <jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content> by 114% (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001 for both), but did not significantly alter 30\u2010day readmission and 30\u2010day and 1\u2010year mortality rates. <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> \u2265\u00a03 <jats:styled-content style=\"fixed-case\">POC<\/jats:styled-content>s increased <jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content> by 162% (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001) and showed an increased 1\u2010year mortality (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study shows that in\u2010hospital medical and surgical complications after surgery for colorectal cancer in patients \u2265\u00a070\u00a0years old are frequent and that complications lead to less favourable outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.13821","type":"journal-article","created":{"date-parts":[[2017,7,22]],"date-time":"2017-07-22T08:02:37Z","timestamp":1500710557000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Postoperative complications in individuals aged 70 and over undergoing elective surgery for colorectal cancer"],"prefix":"10.1111","volume":"19","author":[{"given":"K.","family":"Fagard","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine University Hospitals Leuven Leuven 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