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The crucial points in the next phase of trials include: patient selection, whether radiotherapy can be omitted altogether and whether chemotherapy can be used to augment the initial response to chemoradiotherapy. Finally, with the emergence of Magnetic Resonance Tumour Regression Grade a reliable method for assessing response after initial chemoradiotherapy, we ask if this can be used to drive the use of further selective chemotherapy to augment response.<\/jats:p>","DOI":"10.1111\/codi.14081","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T23:33:21Z","timestamp":1527809601000},"page":"56-60","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Session 2: Are we ready for primary chemotherapy in rectal cancer: who, when, why?"],"prefix":"10.1111","volume":"20","author":[{"given":"U. 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