{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T15:29:57Z","timestamp":1766158197333,"version":"3.37.3"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T00:00:00Z","timestamp":1532304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009336","name":"Bengt Ihres Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Visceral obesity is associated with perioperative and postoperative complications in colorectal surgery. We aimed to investigate the association between the perirenal fat surface area (<jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content>) and postoperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Data on 610 patients undergoing curative, elective colon cancer resection between 2006 and 2016 at Stockholm South General Hospital were retrieved from a local quality register. We assessed perioperative and postoperative outcomes using a multinomial regression model adjusted for age, sex, American Society of Anesthesiologists classification and surgical approach (open\/laparoscopy) in relation to <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> could be measured in 605 patients; the median area was 24 cm<jats:sup>2<\/jats:sup>. Patients with <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> \u2265 40 cm<jats:sup>2<\/jats:sup> had longer operation time (median 223 <jats:italic>vs<\/jats:italic> 184 min), more intra\u2010operative bleeding (250 <jats:italic>vs<\/jats:italic> 125 ml), reoperations (11% <jats:italic>vs<\/jats:italic> 6%), surgical complications (27% <jats:italic>vs<\/jats:italic> 13%) and nonsurgical infectious complications (16% <jats:italic>vs<\/jats:italic> 9%) than patients with <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> &lt; 40 cm<jats:sup>2<\/jats:sup>, but there were no differences in the need for intensive care or duration of hospital stay. The multivariate analyses revealed an increased risk of any complication [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.68 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.1\u20132.6)], which was even more pronounced for moderate complications [Clavien\u2013Dindo <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OR<\/jats:styled-content> 2.14 (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.2\u20132.4]; Clavien\u2013Dindo <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OR<\/jats:styled-content> 2.35 (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.0\u20135.5)] in patients with <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> \u2265 40 <jats:italic>vs<\/jats:italic> &lt; 40 cm<jats:sup>2<\/jats:sup>. The absolute risk of complications was similar in men and women with <jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content> \u2265 40 cm<jats:sup>2<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PRF<\/jats:styled-content>, an easily measured indirect marker of visceral obesity, was associated with overall and moderate complications in men and women and could serve as a useful tool in the assessment of preoperative risk.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14322","type":"journal-article","created":{"date-parts":[[2018,6,29]],"date-time":"2018-06-29T11:27:41Z","timestamp":1530271661000},"page":"1078-1087","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Perirenal fat surface area as a risk factor for perioperative difficulties and 30\u2010day postoperative complications in elective colon cancer surgery"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6115-4909","authenticated-orcid":false,"given":"O.","family":"der Hagopian","sequence":"first","affiliation":[{"name":"Department of Clinical Science and Education S\u00f6dersjukhuset (KI S\u00d6S) Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Dahlberg","sequence":"additional","affiliation":[{"name":"Department of Surgery S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Heinius","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education S\u00f6dersjukhuset (KI S\u00d6S) Karolinska Institutet Stockholm Sweden"},{"name":"Department of Surgery S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Nordberg","sequence":"additional","affiliation":[{"name":"Bilddiagnostiskt Centrum (BDC) S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Gustafsson","sequence":"additional","affiliation":[{"name":"Bilddiagnostiskt Centrum (BDC) S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Nordenvall","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"},{"name":"Center for Digestive Disease Division of Coloproctology Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Sandblom","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education S\u00f6dersjukhuset (KI S\u00d6S) Karolinska Institutet Stockholm Sweden"},{"name":"Department of Surgery S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Farahnak","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education S\u00f6dersjukhuset (KI S\u00d6S) Karolinska Institutet Stockholm Sweden"},{"name":"Department of Surgery S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5. H.","family":"Everhov","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education S\u00f6dersjukhuset (KI S\u00d6S) Karolinska Institutet Stockholm Sweden"},{"name":"Department of Surgery S\u00f6dersjukhuset Stockholm Sweden"},{"name":"Clinical Epidemiology Unit Department of Medicine Solna Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237249"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000407"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181f2f202"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000312"},{"key":"e_1_2_12_6_1","unstructured":"Koloncancer 2016 Regionalt cancercentrum Norr Ume\u00e5"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2008.08.032"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2280-0"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000029"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-010-0963-0"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-2045-9"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00033.2011"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-015-3085-6"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1803-9"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-008-9395-0"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2174-1"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.12.012"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000261"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2016.09.001"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-017-1636-z"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6672-4"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00731.x"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/014107680710001113"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-009-9350-y"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2006.03780.x"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318262a6cd"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000973"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31817bbe3a"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.03079.x"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00104-009-1725-9"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-011-1655-y"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00357.2003"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.072"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-016-2532-7"},{"key":"e_1_2_12_36_1","first-page":"DZWD","article-title":"[Laparoscopic colorectal surgery no longer the ugly duckling \u2013 proportion of laparoscopic operations increasing in Sweden.]","volume":"113","author":"Matthiessen P","year":"2016","journal-title":"L\u00e4kartidningen"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0167271"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182708cc5"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.068189"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182988d59"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.222"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.14322","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.14322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T15:52:51Z","timestamp":1694793171000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.14322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,23]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/codi.14322"],"URL":"https:\/\/doi.org\/10.1111\/codi.14322","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"type":"print","value":"1462-8910"},{"type":"electronic","value":"1463-1318"}],"subject":[],"published":{"date-parts":[[2018,7,23]]},"assertion":[{"value":"2018-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}