{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T04:00:49Z","timestamp":1784606449669,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T00:00:00Z","timestamp":1533254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim was to determine the prevalence and risk factors of anal symptoms prepartum and postpartum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A prospective observational cohort study was carried out in Ghent University Hospital, Belgium. Ninety\u2010four pregnant women between their 19th and 25th week of pregnancy were included. An anal symptom questionnaire was filled in at four different times: in the second and third trimester, immediately postpartum and 3 months postpartum. Descriptive data were obtained from patient files. A proctological diagnosis was presumed on the basis of combined symptoms (i.e. rectal bleeding, anal pain and swelling). Constipation was defined by the Rome III criteria. Risk factors were identified using multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010eight per cent of the patients developed anal symptoms. The most prevalent symptom was anal pain. Constipation was reported by 60.7% during the study period. Seven women (7.9%) suffered from faecal incontinence. The most prevalent diagnoses were haemorrhoidal thrombosis (immediately postpartum), haemorrhoidal prolapse (in the third trimester and immediately postpartum) and anal fissure (not episode related). The two independent risk factors for anal complaints were constipation, with a 6.3 odds ratio (95% CI 2.08\u201319.37), and a history of anal problems, with a 3.9 odds ratio (95% CI 1.2\u201313). The Bristol Stool Chart was shown to be a reliable indicator in pregnancy and postpartum as significant correlations were observed in all study periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Two\u2010thirds of pregnant women have anal symptoms during pregnancy and postpartum, especially haemorrhoidal complications and anal fissure. The most important risk factor is constipation. The prevention of constipation in pregnant women is therefore highly recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14324","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T19:19:46Z","timestamp":1530645586000},"page":"1109-1116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Anorectal symptoms during pregnancy and postpartum: a prospective cohort study"],"prefix":"10.1111","volume":"20","author":[{"given":"K.","family":"Ferdinande","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ghent University Hospital Ghent University Gent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Dorreman","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Ghent University Hospital Ghent University Gent 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