{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T13:07:31Z","timestamp":1789650451504,"version":"4.0.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013226","name":"Les Laboratories Pierre Fabre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Current questionnaires designed to evaluate the burden of haemorrhoidal disease ignore symptoms such as bleeding, pain and itching. A specific questionnaire is needed to evaluate the global impact of anal disorders on patients\u2019 daily lives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We developed a questionnaire (<jats:styled-content style=\"fixed-case\">HEMO<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FISS<\/jats:styled-content>\u2010QoL) to assess the symptom burden of anal disorders and administered it to 256 patients (mean age 46.2\u00a0years; men 60.4%) with haemorrhoidal disease (67.2%), anal fissure (29.3%) or both (3.5%). Psychometric properties were evaluated by testing the acceptability, construct validity and reliability of the questionnaire. Principal components and multi\u2010trait analyses were used to identify dimensions and to assess construct validity. Backward Cronbach alpha curves and a graded response model were used to reduce the number of items\u00a0and\u00a0modalities. External validity was evaluated against <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 and the Psychological Global Well\u2010Being Index\u00a0(<jats:styled-content style=\"fixed-case\">PGWBI<\/jats:styled-content>) using Spearman's correlation coefficient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Principal component analysis defined four dimensions: physical disorders, psychology, defaecation and sexuality. The number of questions was reduced from 38 to 23. The <jats:styled-content style=\"fixed-case\">HEMO<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FISS<\/jats:styled-content>\u2010QoL scores correlated well with those of the <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201012 and <jats:styled-content style=\"fixed-case\">PGWBI<\/jats:styled-content> (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). Cronbach's coefficients (all\u00a0&gt;\u00a00.7) reflected good internal reliability of the different dimensions. The total score increased with the severity of the anal disorders and with their consequences (days off work and personal spending related to the disease).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">HEMO<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FISS<\/jats:styled-content>\u2010QoL questionnaire reliably evaluates the global impact of haemorrhoids and anal fissures on patients\u2019 daily lives. This simple tool may prove useful for treatment evaluation in clinical trials and daily practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14393","type":"journal-article","created":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T10:50:27Z","timestamp":1535799027000},"page":"48-58","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Psychometric properties of a questionnaire (HEMO\u2010FISS\u2010QoL) to evaluate the burden associated with haemorrhoidal disease and anal fissures"],"prefix":"10.1111","volume":"21","author":[{"given":"L.","family":"Abramowitz","sequence":"first","affiliation":[{"name":"AP\u2010HP Proctologie M\u00e9dico Chirurgicale du Service de Gastroent\u00e9rologie CHU Bichat Paris France"},{"name":"Clinique Blomet Ramsay GDS GREP (Groupe de Recherche en Proctologie de la SNFCP) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Bouchard","sequence":"additional","affiliation":[{"name":"Service de Proctologie H\u00f4pital Bagatelle Talence France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Siproudhis","sequence":"additional","affiliation":[{"name":"Service de Gastroent\u00e9rologie et Groupe Imphy CIC1414 CHU Pontchaillou Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Trompette","sequence":"additional","affiliation":[{"name":"AP\u2010HP Proctologie M\u00e9dico Chirurgicale du Service de Gastroent\u00e9rologie CHU Bichat Paris France"},{"name":"Clinique Blomet Ramsay GDS GREP (Groupe de Recherche en Proctologie de la SNFCP) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Pillant","sequence":"additional","affiliation":[{"name":"Service de Proctologie Groupe Hospitalier Saint Joseph Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Bord","sequence":"additional","affiliation":[{"name":"Polyclinique de Saint Roch Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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