{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T04:25:59Z","timestamp":1784262359185,"version":"3.55.0"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T00:00:00Z","timestamp":1547251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess short\u2010 and long\u2010term outcomes of redo ileal pouch\u2010anal anastomosis (redo\u2010IPAA) for failed IPAA, comparing them with those of successful IPAA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a case\u2013control study. Data were collected retrospectively from prospectively maintained databases from two tertiary care centres. Patients who had a redo\u2010IPAA between 1999 and 2016 were identified and matched (1:2) with patients who had a primary IPAA (p\u2010IPAA), according to diagnosis, age and body mass index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010nine redo\u2010IPAAs (16 transanal and 23 abdominal procedures) were identified, and were matched with 78 p\u2010IPAAs. After a mean follow\u2010up of 56\u00a0\u00b1\u00a051\u00a0 (2.6\u2013190) months, failure rates after transanal and abdominal approaches were 50% and 15%, respectively. Reoperation after the transanal approach was higher than after p\u2010IPAA (69% <jats:italic>vs<\/jats:italic> 7%; <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.001). No differences were noted between the abdominal approach for redo\u2010IPAA and p\u2010IPAA in terms of morbidity (61% for redo\u2010IPAA <jats:italic>vs<\/jats:italic> 38% for p\u2010IPAA; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.06), major morbidity (9% <jats:italic>vs<\/jats:italic> 8%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.96), anastomotic leakage (13% <jats:italic>vs<\/jats:italic> 10%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.74), mean daily bowel movements (6 <jats:italic>vs<\/jats:italic> 5.5; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.68), night\u2010time bowel movements (1.2 <jats:italic>vs<\/jats:italic> 1; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.51), faecal incontinence (13% <jats:italic>vs<\/jats:italic> 7%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.40), urgency (31% <jats:italic>vs<\/jats:italic> 27%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.59), use of anti\u2010diarrhoeal drugs (47% <jats:italic>vs<\/jats:italic> 37%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.70), mean Cleveland Global Quality\u2010of\u2010Life score (7 <jats:italic>vs<\/jats:italic> 7; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.83) or sexual function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The abdominal approach for redo\u2010IPAA is justified in cases of pouch failure because it achieves functional results comparable with those observed after p\u2010IPAA, without higher postoperative morbidity. The transanal approach should be chosen sparingly.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14484","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T15:10:07Z","timestamp":1545232207000},"page":"326-334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Redo ileal pouch\u2010anal anastomosis: outcomes from a case\u2013controlled study"],"prefix":"10.1111","volume":"21","author":[{"given":"C.","family":"Rossi","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery H\u00f4pital Nord Assistance Publique\u2010H\u00f4pitaux de Marseille Aix\u2010Marseille Universit\u00e9 Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Beyer\u2010Berjot","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery H\u00f4pital Nord Assistance Publique\u2010H\u00f4pitaux de Marseille 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