{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T17:47:33Z","timestamp":1776448053181,"version":"3.51.2"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T00:00:00Z","timestamp":1558137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Faecal incontinence is frequent in the elderly. Little is currently known about the efficacy of sacral nerve modulation (SNM) in the elderly. The present study aimed to assess the impact of age on the outcome of SNM and on the surgical revision and explantation rates by comparing the results of a large data set of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Prospectively collected data from patients who underwent an implant procedure between January 2010 and December 2015 in seven French centres were retrospectively evaluated. In total, 352 patients [321 women; median age (range): 63\u00a0(24\u201386) years] were included. Clinically favourable and unfavourable outcomes, and surgical revision and explantation rates, were compared according to the age of the patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A similar outcome was observed when comparing patients &lt;\u00a070\u00a0years and \u2265\u00a070\u00a0years (a favourable outcome in 79.2% and 76.2%, respectively, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.89). The probability of a successful treatment as a function of time was similar for the two age groups (&lt;\u00a070\u00a0years and \u2265\u00a070\u00a0years, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.54). The explantation and revision rates were not influenced by age (explantation rate: 17% in patients &lt;\u00a070\u00a0years <jats:italic>vs<\/jats:italic> 14% in patients \u2265\u00a070\u00a0years, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.89; and revision rate: 42% in patients &lt;\u00a070\u00a0years <jats:italic>vs<\/jats:italic> 40% in patients \u2265\u00a070\u00a0years, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.89). The probability of explantation as a function of time was similar for the two age groups (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.82). The limitations of this study were its retrospective status, the rate of loss at follow\u2010up and different durations of patient follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that patients \u2265\u00a070\u00a0years suffering from faecal incontinence benefit from SNM with a similar risk as a younger population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14649","type":"journal-article","created":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T13:47:29Z","timestamp":1555336049000},"page":"1058-1066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Sacral nerve modulation for faecal incontinence: influence of age on outcomes and complications. A multicentre study"],"prefix":"10.1111","volume":"21","author":[{"given":"D.","family":"Mege","sequence":"first","affiliation":[{"name":"Department of Digestive Surgery Assistance Publique H\u00f4pitaux de Marseille Timone University Hospital Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Meurette","sequence":"additional","affiliation":[{"name":"Digestive and Endocrine Surgery Clinic Diseases of the Digestive Tract Institute University Hospital of Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Brochard","sequence":"additional","affiliation":[{"name":"Diseases of the Digestive Tract Department Functional Digestive Explorations Division CHU Pontchaillou, CIC1414 INPHY, INSERM U1241 Universit\u00e9 de Rennes 1 Rennes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Damon","sequence":"additional","affiliation":[{"name":"Digestive Physiology University Hospital of Lyon Hospices Civils de Lyon H\u00f4pital E Herriot Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Lambrescak","sequence":"additional","affiliation":[{"name":"Department of Coloproctology Groupe Hospitalier Diaconesses Croix Saint\u2010Simon Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.\u2010L.","family":"Faucheron","sequence":"additional","affiliation":[{"name":"Department of Surgery Colorectal Unit Michallon University Hospital Grenoble France"},{"name":"University Grenoble Alps UMR 5525 CNRS TIMC\u2010IMAG Grenoble France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Wyart","sequence":"additional","affiliation":[{"name":"Digestive and Endocrine Surgery Clinic Diseases of the Digestive Tract Institute University Hospital of Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.\u2010A.","family":"Lehur","sequence":"additional","affiliation":[{"name":"Digestive and Endocrine Surgery Clinic Diseases of the Digestive Tract Institute University Hospital of Nantes Nantes France"},{"name":"Department of General Surgery Ospedale Civico di Lugano Lugano Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Sielezneff","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery Assistance Publique H\u00f4pitaux de Marseille Timone University Hospital Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Siproudhis","sequence":"additional","affiliation":[{"name":"Diseases of the Digestive Tract Department Functional Digestive Explorations Division CHU Pontchaillou, CIC1414 INPHY, INSERM U1241 Universit\u00e9 de Rennes 1 Rennes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Mion","sequence":"additional","affiliation":[{"name":"Digestive Physiology University Hospital of Lyon Hospices Civils de Lyon H\u00f4pital E Herriot Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Etienney","sequence":"additional","affiliation":[{"name":"Department of Coloproctology Groupe Hospitalier Diaconesses Croix Saint\u2010Simon Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Houivet","sequence":"additional","affiliation":[{"name":"Biostatistics Unit INSERM CIC 1404 Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Bridoux","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery Normandie Univ UNIROUEN Inserm U1073 Rouen University Hospital Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.\u2010M.","family":"Leroi","sequence":"additional","affiliation":[{"name":"Department of Digestive Physiology and CIC\u2010CRB 1404 Normandie Univ UNIROUEN, Inserm U1073 Rouen University Hospital Rouen France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.11.009"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp067041"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1995.tb07046.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.284"},{"key":"e_1_2_10_6_1","first-page":"CD004464","article-title":"Sacral nerve stimulation for faecal incontinence and constipation in adults","volume":"24","author":"Thaha MA","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02623.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182270af1"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9740"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000115"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-014-1870-6"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15999-0"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31829d3969"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2013.10.003"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02568.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22268"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.02.020"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181cf8ed0"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e31822155e9"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318210f1f4"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surge.2017.08.006"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00516-4"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.14649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.14649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/codi.14649","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.14649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T07:32:06Z","timestamp":1694331126000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.14649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,18]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/codi.14649"],"URL":"https:\/\/doi.org\/10.1111\/codi.14649","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,18]]},"assertion":[{"value":"2019-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}