{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T08:46:19Z","timestamp":1694335579963},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T00:00:00Z","timestamp":1563148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aims to determine the prevalence of incisional hernia (IH) and enterocutaneous fistula (ECF) in patients with intestinal failure (IF) referred to a tertiary centre and to identify factors associated with their development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective case note review was undertaken of a prospectively maintained database of all patients on home parenteral nutrition between 2011 and 2016 at a UK tertiary referral centre for IF. Risk factors were identified using binary logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The database search identified 447 patients, of whom 349 (78.1%) had surgery prior to developing IF. Eighty\u2010one (23.2%) patients had an IH and 123 (35.2%) had an ECF at the time of referral. Of these, 51 (14.6%) had both IH and ECF. IH was associated with a high body mass index (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.05), a history of a major surgical complication resulting in IF (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.01), previous emergency surgery (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04), increasing number of operations (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02) and surgical site infection (SSI; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.01). ECF was associated with complications relating to earlier surgery. (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a0.001), previous treatment with an open abdomen (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.03), SSI (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001), intra\u2010abdominal collection (<jats:italic>P\u00a0<\/jats:italic>\u2264\u00a00.001) and anastomotic leak (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this series, patients with IF had a prevalence of IH which was more than double that expected following elective laparotomy (about 10%) and one in three had an ECF. Risk factors for IH and ECF are discussed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14735","type":"journal-article","created":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T08:59:19Z","timestamp":1561021159000},"page":"1288-1295","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incisional hernia and enterocutaneous fistula in patients with chronic intestinal failure: prevalence and risk factors in a cohort of patients referred to a tertiary centre"],"prefix":"10.1111","volume":"21","author":[{"given":"J. D.","family":"Hodgkinson","sequence":"first","affiliation":[{"name":"St Mark's Hospital and Academic Institute Harrow UK"},{"name":"Department of Surgery and Cancer Imperial College London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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