{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:28:56Z","timestamp":1790371736316,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T00:00:00Z","timestamp":1572220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Sacral nerve stimulation (SNS) for faecal incontinence (FI) at subsensory amplitudes as low as 50% of the sensory threshold has been found to be effective at 3 months\u2019 follow\u2010up. Furthermore, alternative pacemaker settings may improve functional outcome in patients with suboptimal treatment efficacy. In this work we aim to explore if sub\u2010sensory stimulation as low as 50% of sensory threshold is effective at 1\u2010year follow\u2010up. We also aimed to investigate if 31\u00a0Hz (frequency) or 90\u00a0\u00b5s (pulse width) stimulation improved treatment efficacy in dissatisfied patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>All patients in whom the stimulation was effective in controlling FI (satisfied group) were encouraged to have the stimulation amplitude reduced. Those in whom the device was less effective (dissatisfied group) were offered alternative frequency settings or pulse width (31\u00a0Hz or 90\u00a0\u00b5s). Patients were follow\u2010up after 12 months and evaluated by a visual analogue scale (VAS) for patient satisfaction, the Cleveland Clinic Continence Score (CCCS), Rockwood Faecal Incontinence Quality of Life Scale (QoL) and a bowel habit diary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and nineteen patients were contacted, with a response rate of 71% (<jats:italic>n<\/jats:italic>\u00a0=\u00a0155). Those who were successfully contacted comprised 110 (71%) patients classed as satisfied and 45 (29%) as dissatisfied. Seventy\u2010five (68%) of the satisfied patients agreed to have their stimulation amplitude reduced. At 1\u2010year follow\u2010up the median amplitude had reduced from 1.5 V [interquartile range (IQR) 0.85\u20132.0 V] to 0.75 V (IQR 0.45\u20131.4 V) (<jats:italic>P<\/jats:italic>\u2010value &lt;\u00a00.001) representing an overall reduction of 39% (6.6\u201362.5%). There were no significant differences in VAS, CCCS or QoL despite subsensory stimulation at 1\u2010year follow\u2010up. In 28% of the dissatisfied patients alternative pacemaker settings improved VAS to satisfactory levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Subsensory stimulation is as effective as stimulation at or above the sensory threshold. High\u2010frequency stimulation (31\u00a0Hz) can improve functional outcome in patients with loss of efficacy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14874","type":"journal-article","created":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T09:03:10Z","timestamp":1570957390000},"page":"310-318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Improved longevity and efficacy of sacral nerve stimulation by simple adjustments at follow\u2010up"],"prefix":"10.1111","volume":"22","author":[{"given":"J.","family":"Duelund\u2010Jakobsen","sequence":"first","affiliation":[{"name":"Pelvic Floor Unit Department of Surgery Aarhus University Hospital Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Buntzen","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit Department of Surgery Aarhus University Hospital Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Laurberg","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit Department of Surgery Aarhus University Hospital Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Lundby","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit Department of Surgery Aarhus University Hospital Aarhus N 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