{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:11:45Z","timestamp":1785449505537,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T00:00:00Z","timestamp":1582243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Anorectal physiology tests provide a functional assessment of the anal canal. The aim of this study was to compare the results generated by standard high\u2010resolution water\u2010perfused manometry (WPM) with the newer THD<jats:sup>\u00ae<\/jats:sup> Anopress manometry system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a prospective observational study. Conventional manometry was carried out using a water\u2010perfused catheter with high\u2010resolution manometry and compared with the Anopress system with air\u2010filled catheters. All patients underwent the two procedures successively in a randomized order. Time to arrive at the resting pressure plateau, resting, squeeze, straining pressure and visual analogue scale (VAS) scores for pain were recorded. A qualitative analysis of the two devices was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between 2016 and 2017, 60 patients were recruited. The time from insertion of the catheter to arriving at the resting pressure plateau was significantly lower with the Anopress compared with WPM: 12\u00a0s [interquartile range (IQR) 10\u201317\u00a0s] versus 100\u00a0s (IQR 67\u2013121\u00a0s) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). A strong correlation between the manometric values of WPM and the Anopress was observed. Both procedures were well tolerated, although the VAS score for insertion of the WPM catheter was significantly higher. The Anopress was easier to use and more time\u2010efficient than the WPM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The pressure values obtained with Anopress correlated well with those of conventional manometry. The Anopress has the advantage of being less time\u2010consuming, user\u2010friendly and better tolerated by patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.14992","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T04:15:56Z","timestamp":1580271356000},"page":"923-930","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Comparison between high\u2010resolution water\u2010perfused anorectal manometry and THD<sup>\u00ae<\/sup> Anopress anal manometry: a prospective observational study"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5759-0345","authenticated-orcid":false,"given":"C. A.","family":"Leo","sequence":"first","affiliation":[{"name":"Sir Alan Park\u2019s Physiology Unit St Mark\u2019s Hospital Academic Institute Harrow UK"},{"name":"Imperial College of London London UK"},{"name":"The Royal London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Cavazzoni","sequence":"additional","affiliation":[{"name":"Santa Maria della Misericordia Hospital Universit\u00e0 degli Studi di Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. M. N.","family":"Leeuwenburgh","sequence":"additional","affiliation":[{"name":"The Royal London Hospital London UK"},{"name":"Haaglanden Medisch Centrum Den Haag The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. P.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Sir Alan Park\u2019s Physiology Unit St Mark\u2019s Hospital Academic Institute Harrow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Dennis","sequence":"additional","affiliation":[{"name":"Sir Alan Park\u2019s Physiology Unit St Mark\u2019s Hospital Academic Institute Harrow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Bassett","sequence":"additional","affiliation":[{"name":"Statsconsultancy Ltd Amersham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. D.","family":"Hodgkinson","sequence":"additional","affiliation":[{"name":"Sir Alan Park\u2019s Physiology Unit St Mark\u2019s Hospital Academic Institute Harrow UK"},{"name":"Imperial College of London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Warusavitarne","sequence":"additional","affiliation":[{"name":"Sir Alan Park\u2019s Physiology Unit St Mark\u2019s Hospital Academic Institute Harrow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Imperial College of London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. J.","family":"Vaizey","sequence":"additional","affiliation":[{"name":"Sir Alan Park\u2019s Physiology Unit St Mark\u2019s Hospital Academic Institute Harrow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2012.18.1.86"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118727072.ch25"},{"key":"e_1_2_10_4_1","first-page":"99","article-title":"Faecal incontinence and constipation","volume":"6","author":"Barrett JA","year":"2004","journal-title":"C J Geriatr Med."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2982.2002.00352.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-88-470-1542-5_60"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000171417"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2018.27"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-015-0067-6"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2010.16.4.437"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm15168"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800760414"},{"key":"e_1_2_10_13_1","unstructured":"THD SpA Italy.THDAnopress[Internet].2018[cited 2019 Mar 26]. Available from:http:\/\/thdanopress.com\/"},{"key":"e_1_2_10_14_1","volume-title":"Manual of Clinical Anorectal Manometry","author":"Cavazzoni E","year":"2017"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm17135"},{"key":"e_1_2_10_16_1","first-page":"8","article-title":"Evaluation of the portable THD \u00ae Anopress device in patients with faecal incontinence","volume":"8","author":"Leo CA","year":"2018","journal-title":"J Dig Dis"},{"key":"e_1_2_10_17_1","unstructured":"VaizeyC.Ano\u2010rectal physiology (ARP): comparison of reproducibility of results between water perfused and solid state catheters (THD Anopress)[Internet].2016[cited 2019 Jan 10]. Available from:https:\/\/www.hra.nhs.uk\/planning-and-improving-research\/application-summaries\/research-summaries\/portable-manometry-anopress-thd-a-pilot-study\/"},{"key":"e_1_2_10_18_1","unstructured":"Royal College of Surgeon U.Commissioning guide : Faecal Incontinence[Internet]. RCS website.2013[cited 2018 Nov 6]. pp.1\u201316. Available from:https:\/\/entuk.org\/professionals\/commissioning\/commissioning"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12038"},{"key":"e_1_2_10_20_1","unstructured":"MMS.MMS Medical Measurement Systems[Internet].2018[cited 2019 Jan 10]. Available from:http:\/\/www.mmsinternational.com\/int\/676\/gastroenterology-hrm"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.1.77"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-09528-8_15"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-006-0245-6"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12397"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13532"},{"key":"e_1_2_10_26_1","first-page":"516","volume-title":"Surgery of the Anus Rectum Colon","author":"Keighley MRB","year":"1993"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.14992","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.14992","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/codi.14992","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.14992","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T21:00:54Z","timestamp":1693947654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.14992"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,21]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1111\/codi.14992"],"URL":"https:\/\/doi.org\/10.1111\/codi.14992","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,21]]},"assertion":[{"value":"2019-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}