{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T22:04:34Z","timestamp":1764540274289},"reference-count":59,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T00:00:00Z","timestamp":1586908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Bowel dysfunction following anterior resection (AR) is termed low anterior resection syndrome. It is unclear whether such dysfunction occurs following other bowel\/pelvic operations as well. This study aimed to characterize and compare bowel dysfunction following AR, right hemicolectomy (RH) and radical cystectomy (RC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A prospective study of consecutive patients undergoing AR, RH and RC (2002\u20132012) was performed at a tertiary referral centre in Sydney, Australia. Outcome measures included (i) patient\u2010reported satisfaction with bowel function, self\u2010described bowel function and self\u2010reported change in bowel function; (ii) objective assessment of bowel function using validated criteria to identify symptoms and stratify patients into those with constipation and\/or faecal incontinence (FI); and (iii) health\u2010related quality of life (SF\u201036v2 Health Survey).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 743 eligible patients, 70% participated [AR, <jats:italic>n<\/jats:italic>\u00a0=\u00a0338, mean age 69.6\u00a0years (SD 11.9), 59% men; RH, <jats:italic>n<\/jats:italic>\u00a0=\u00a0150, 75.8\u00a0years (SD 10.5), 54% men; RC, <jats:italic>n<\/jats:italic>\u00a0=\u00a034, 71.1\u00a0years (SD 14.1), 71% men]. AR patients were three times more likely to report change in bowel function post\u2010surgery and self\u2010judged their bowel function as abnormal more frequently (64%) than RH patients (35%) and RC patients (35%) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01). AR patients were four times more likely to meet criteria for concomitant constipation and FI. Patients with concomitant constipation and FI had lower physical and mental SF\u201036v2 scores (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Bowel dysfunction occurred after RH and RC but rates were higher following AR. This suggests that low anterior resection syndrome occurs due to a direct impact of partial\/complete loss of the rectum rather than just due to loss of bowel length and\/or the consequence(s) of pelvic dissection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.15041","type":"journal-article","created":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T02:30:27Z","timestamp":1584412227000},"page":"1336-1347","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Patient\u2010reported and physician\u2010recorded bowel dysfunction following colorectal resection and radical cystectomy: a prospective, comparative study"],"prefix":"10.1111","volume":"22","author":[{"given":"K.\u2010S.","family":"Ng","sequence":"first","affiliation":[{"name":"Academic Colorectal Unit Sydney Medical School \u2013 Concord University of Sydney Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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