{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:53:41Z","timestamp":1747184021403,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T00:00:00Z","timestamp":1589500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Thorough assessment of obstructed defaecation syndrome (ODS) is imperative for the selection of treatment options. The present study aimed to examine the utility of the Mansoura Numeroalphabetic Constipation Score (MNCS) in distinguishing patients with ODS from healthy control subjects and in predicting the outcome of treatment of ODS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with ODS associated with anterior rectocele and\/or rectoanal intussusception were assessed with the MNCS at the first visit to the clinic. All patients were offered conservative treatment for 3\u00a0months and patients who improved were continued on conservative treatment for six more months while patients who failed were treated surgically. The MNCS was reassessed at the end of follow\u2010up in both groups. A cohort of healthy controls was compared to ODS patients with regard to age, sex and baseline MNCS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 124 ODS patients and 53 healthy controls were included. The ODS patients had a significantly higher baseline MNCS than controls (9.5\u00a0\u00b1\u00a01.5 <jats:italic>vs<\/jats:italic> 0.76\u00a0\u00b1\u00a00.71, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). Forty of 124 patients improved after conservative management and showed a significant decrease in MNCS (6.9\u00a0\u00b1\u00a01.08 to 3.1\u00a0\u00b1\u00a01.2, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). Eighty\u2010four (67.8%) patients failed to respond to conservative measures and were surgically treated, 77 (91.6%) of whom showed significant improvement in symptoms postoperatively while seven (8.4%) failed to improve; the difference in postoperative MNCS between the two groups was significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The MNCS successfully distinguished ODS patients from controls and was able to predict the outcome of ODS treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.15082","type":"journal-article","created":{"date-parts":[[2020,4,25]],"date-time":"2020-04-25T06:25:33Z","timestamp":1587795933000},"page":"1348-1358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Utility of the Mansoura Numeroalphabetic Constipation Score in detection of obstructed defaecation syndrome and prediction of the outcome of treatment"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7854-5244","authenticated-orcid":false,"given":"S.","family":"Emile","sequence":"first","affiliation":[{"name":"Colorectal Surgery Unit General Surgery Department Mansoura University Hospitals Mansoura University Mansoura City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0358-2398","authenticated-orcid":false,"given":"M.","family":"Shalaby","sequence":"additional","affiliation":[{"name":"Colorectal Surgery Unit General Surgery Department Mansoura University Hospitals Mansoura University Mansoura City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Elshobaky","sequence":"additional","affiliation":[{"name":"Colorectal Surgery Unit General Surgery Department Mansoura University Hospitals Mansoura University Mansoura City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Khafagy","sequence":"additional","affiliation":[{"name":"Colorectal Surgery Unit General Surgery Department Mansoura University Hospitals Mansoura University Mansoura City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Farid","sequence":"additional","affiliation":[{"name":"Colorectal Surgery Unit General Surgery Department Mansoura University Hospitals Mansoura University Mansoura City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-8-5"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02554713"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.061"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1301753"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1586\/egh.11.53"},{"key":"e_1_2_9_7_1","first-page":"264","article-title":"Mansoura Numeroalphabetic Constipation Score in obstructed defecation syndrome (ODS): validation of a new score","volume":"3","author":"Emile S","year":"2015","journal-title":"Int J Adv Res"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199579624.001.0001"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-13327-5_154"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i4.1053"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1301756"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/10790268.2003.11753709"},{"key":"e_1_2_9_13_1","first-page":"63","article-title":"Functional disorders: rectocele","volume":"30","author":"Mustain WC","year":"2017","journal-title":"Clin Colon Rectal Surg"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-84882-756-1_11"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i14.1555"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2004.00758.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00341233"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v7.i3.453"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-006-0244-7"},{"key":"e_1_2_9_20_1","first-page":"103","volume-title":"Constipation: Etiology, Evaluation and Management","author":"Devroede G","year":"1995"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-006-0315-9"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13574"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-016-3299-4"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0609-7"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0582-3"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-019-01944-9"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2011.17.3.211"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.15082","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.15082","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/codi.15082","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.15082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T08:31:28Z","timestamp":1693729888000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.15082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,15]]},"references-count":26,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/codi.15082"],"URL":"https:\/\/doi.org\/10.1111\/codi.15082","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"type":"print","value":"1462-8910"},{"type":"electronic","value":"1463-1318"}],"subject":[],"published":{"date-parts":[[2020,5,15]]},"assertion":[{"value":"2019-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}