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With the ongoing need for urgent and emergency colorectal surgery, including surgery for colorectal cancer, several questions pertaining to operating room (OR) utilization and techniques needed to be rapidly addressed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This manuscript discusses knowledge related to the critical considerations of patient and caregiver safety relating to personal protective equipment (PPE) and the operating room environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the COVID\u201019 pandemic, additional personal protective equipment (PPE) may be required contingent upon local availability of COVID\u201019 testing and the incidence of known COVID\u201019 infection in the respective community. In addition to standard COVID\u201019 PPE precautions, a negative\u2010pressure environment, including an OR, has been recommended, especially for the performance of aerosol\u2010generating procedures (AGPs). Hospital spaces ranging from patient wards to ORs to endoscopy rooms have been successfully converted from standard positive\u2010pressure to negative\u2010pressure spaces. Another important consideration is the method of surgical access; specifically, minimally invasive surgery with pneumoperitoneum is an AGP and thus must be carefully considered. Current debate centres around whether it should be avoided in patients known to be infected with SARS\u2010CoV\u20102 or whether it can be performed under precautions with safety measures in place to minimize exposure to aerosolized virus particles. Several important lessons learned from pressurized intraperitoneal aerosolized chemotherapy procedures are demonstrated to help improve our understanding and management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This paper evaluates the issues surrounding these challenges including the OR environment and AGPs which are germane to surgical practices around the world. Although there is no single universally agreed upon set of answers, we have presented what we think is a balanced cogent description of logical safe approaches to colorectal surgery during the COVID\u201019 pandemic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.15112","type":"journal-article","created":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T19:56:00Z","timestamp":1588449360000},"page":"635-640","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["COVID\u201019: impact on colorectal surgery"],"prefix":"10.1111","volume":"22","author":[{"given":"S. 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