{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:46:51Z","timestamp":1791928011198,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T00:00:00Z","timestamp":1597795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this work was to compare the outcomes of extended right hemicolectomy (ERH), left hemicolectomy (LH) and segmental colectomy (SC) for the surgical management of splenic flexure tumours.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>In compliance with PRISMA statement standards, a systematic review was performed to identify all studies comparing outcomes of ERH, LH and SC for the surgical management of splenic flexure tumours. Primary outcomes included anastomotic leakage and all postoperative complications. The secondary outcomes included operative time, R0 resection, number of harvested lymph nodes, &gt;\u00a012 harvested lymph nodes, severe complications, postoperative mortality, paralytic ileus, wound infection, pancreatic fistula, intra\u2010abdominal abscess, need for reoperation, length of hospital stay, 5\u2010year overall survival and 5\u2010year disease\u2010free survival. The ROBINS\u2010I tool and GRADE system were used to assess the risk of bias and certainty of evidence, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Analysis of 956 patients from seven observational studies showed that ERH was associated with more paralytic ileus than LH (OR 2.74,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.002) and SC (OR 6.67,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001) and the operative time was shorter in SC than in ERH (mean difference 25.48,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001) and LH (mean difference \u221217.94,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.0002). There were no differences between ERH, LH and SC in terms of anastomotic leakage, postoperative complications, R0 resection, severe complications, postoperative mortality, wound infection, pancreatic fistula, intra\u2010abdominal abscess, need for reoperation, length of hospital stay, &gt;\u00a012 harvested lymph nodes, 5\u2010year overall survival and 5\u2010year disease\u2010free survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The available evidence, limited to observational studies, suggests that there is no difference between ERH, LH and SC in terms of postoperative morbidity and mortality, lymph node yield and cancer survival. Randomized controlled trials are required for definite conclusions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.15292","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T16:16:00Z","timestamp":1596644160000},"page":"1885-1907","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Comparison of extended right hemicolectomy, left hemicolectomy and segmental colectomy for splenic flexure colon cancer: a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3294-4335","authenticated-orcid":false,"given":"S.","family":"Hajibandeh","sequence":"first","affiliation":[{"name":"Department of Colorectal and General Surgery Glan Clwyd Hospital Rhyl UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hajibandeh","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Sandwell and West Birmingham Hospitals NHS Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of General Surgery North Manchester General Hospital Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Zubairu","sequence":"additional","affiliation":[{"name":"Department of General Surgery North Manchester General Hospital Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Akbar","sequence":"additional","affiliation":[{"name":"Department of Colorectal and General Surgery Glan Clwyd Hospital Rhyl UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Maw","sequence":"additional","affiliation":[{"name":"Department of Colorectal and General Surgery Glan Clwyd Hospital Rhyl UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005350070076"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-011-1292-7"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02053691"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2010.12.004"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2012.03.054"},{"key":"e_1_2_11_7_1","first-page":"1577","article-title":"Subtotal colectomy for the treatment of obstructive left colon cancer. 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