{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:46:19Z","timestamp":1789469179433,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T00:00:00Z","timestamp":1601942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Fistula\u2010in\u2010ano (FIA) is an anomalous passage between perianal skin and the anal canal or the rectum that presents many management difficulties. Ligation of intersphincteric fistula tract (LIFT) was introduced as a cost\u2010effective sphincter\u2010saving procedure with a reported success rate of 94.4%. Unfortunately, this procedure is technically challenging, and recently submucosal ligation of fistula tract (SLOFT), a simplification of LIFT, was proposed. Our aim was to assess the SLOFT technique over a longer follow\u2010up period to determine its effectiveness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A prospective observational study was performed in 47 patients with FIA treated by SLOFT from September 2017 to February 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 47 patients, of whom 33(70.2%) were men. The median age was 39\u00a0years (range 30\u201350\u00a0years). All the patients had primary FIA of cryptoglandular origin. The patients were followed up for 1\u00a0year and were postoperatively assessed at 2, 4, 12 and 24\u00a0weeks and 1\u00a0year. The median body mass index was 27.3\u00a0kg\/m<jats:sup>2<\/jats:sup> (range 24.3\u201329.4\u00a0kg\/m<jats:sup>2<\/jats:sup>) and the median duration of surgery was 15\u00a0min (range 13\u201320\u00a0min). Most (83.0%) of the fistulas were trans\u2010sphincteric. The success rates at the end of 24\u00a0weeks and 1\u00a0year were 87.2% and 80.9%, respectively. No postoperative incontinence was recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our series the success rate of SLOFT was 80.9%. There were no sphincter\u2010related complications. Repeat SLOFT was feasible for cases of recurrence. Therefore, SLOFT should be considered an alternative sphincter\u2010saving procedure to LIFT for the management of FIA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.15305","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T02:52:21Z","timestamp":1597200741000},"page":"2199-2203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A prospective evaluation of the outcome of submucosal ligation of fistula tract"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8604-8918","authenticated-orcid":false,"given":"N. K.","family":"Raja Ram","sequence":"first","affiliation":[{"name":"National University of Malaysia Medical Centre Kuala Lumpur Malaysia"},{"name":"Sultanah Aminah Hospital Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. K.","family":"Chan","sequence":"additional","affiliation":[{"name":"Sultanah Aminah Hospital Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. F.","family":"Md Nor","sequence":"additional","affiliation":[{"name":"Sultanah Aminah Hospital Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Sagap","sequence":"additional","affiliation":[{"name":"National University of Malaysia Medical Centre Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0055-3"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13162"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-1318.2003.00459.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13330"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-009-0522-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-014-1183-3"},{"key":"e_1_2_9_8_1","first-page":"42","article-title":"Submucosal Ligation of Fistula Tract (SLOFT) for ano\u2010rectal fistula: an effective and easy technique","volume":"20","author":"Pathak DU","year":"2014","journal-title":"Ambulatory Surg"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01483.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/1117-6806.169818"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e318278164c"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-008-9354-9"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12030"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181f2e9cd"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.15305","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.15305","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/codi.15305","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.15305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T16:45:19Z","timestamp":1693327519000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.15305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,6]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/codi.15305"],"URL":"https:\/\/doi.org\/10.1111\/codi.15305","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,6]]},"assertion":[{"value":"2020-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}