{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:43:44Z","timestamp":1787316224862,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T00:00:00Z","timestamp":1621123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009491","name":"St Mark's Hospital Foundation","doi-asserted-by":"publisher","award":["Seedcorn grant to the Intestinal Imaging Centre"],"award-info":[{"award-number":["Seedcorn grant to the Intestinal Imaging Centre"]}],"id":[{"id":"10.13039\/501100009491","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Anastomotic leak causes significant morbidity for patients undergoing pelvic intestinal surgery. Fluoroscopic assessment of anastomotic integrity using water\u2010soluble contrast enema (WSCE) is of questionable benefit over examination alone. We hypothesized that MRI\u2010enema may be more accurate. The aim of this study was to compare MRI\u2010enema with fluoroscopic WSCE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Patients referred for WSCE with pelvic intestinal anastomosis and defunctioning ileostomy (including patients with suspected or known leaks) were invited to participate. WSCE and MRI\u2010enema were undertaken within 48\u00a0h of each other. MRI sequences were performed before, during and immediately after the introduction of 400\u00a0ml of 1% gadolinium contrast solution per anus. MRI examinations were reported to protocol by two blinded gastrointestinal radiologists. A Likert\u2010scale patient questionnaire was administered to compare patient experience. Follow\u2010up was &gt;12\u00a0months after ileostomy reversal. Anastomotic leak was determined by unblinded consensus of examination and radiological findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen patients were recruited, with a median age of 39\u00a0years (range 22\u201369). Ten were men, 11 had ileoanal pouch formation and five had low anterior resection. Five patients had anastomotic leak identified by MRI and four by WSCE. The radial location of the anastomotic defect was identified in all five patients by MRI versus two on WSCE. MRI revealed additional information including contents of a widened presacral space. Patient experience was equivalent. Eleven patients eventually had ileostomy reversal without complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MRI\u2010enema is a feasible and tolerable alternative to WSCE and offers greater anatomical detail in the context of pelvic intestinal anastomotic leak. Larger prospective studies are required to define its potential role in the UK National Health Service.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.15688","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T10:31:21Z","timestamp":1619433081000},"page":"1890-1899","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["MRI\u2010enema for the assessment of pelvic intestinal anastomotic integrity"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8265-7641","authenticated-orcid":false,"given":"Guy","family":"Worley","sequence":"first","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"},{"name":"Department of Surgery and Cancer Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Burling","sequence":"additional","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"},{"name":"Department of Surgery and Cancer Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Corr","sequence":"additional","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Clark","sequence":"additional","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"},{"name":"Department of Surgery and Cancer Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Baldwin\u2010Cleland","sequence":"additional","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Faiz","sequence":"additional","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"},{"name":"Department of Surgery and Cancer Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Jenkins","sequence":"additional","affiliation":[{"name":"St Mark\u2019s Hospital Harrow UK"},{"name":"Department of Surgery and Cancer Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","unstructured":"RahbariNN.Definition and grading of anastomotic leakage following anterior resection of the rectum\u202f: a proposal by the International Study Group of Rectal 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