{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T19:24:04Z","timestamp":1794338644244,"version":"4.9.0"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,6,27]],"date-time":"2021-06-27T00:00:00Z","timestamp":1624752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>As populations age and cancer management improves, long\u2010term survivorship and quality\u2010of\u2010life (QOL) outcomes are becoming equally important as oncological results. Data from Asian populations are scarce. We aimed to evaluate the sexual health, gastrointestinal function and QOL amongst colorectal cancer survivors in a tertiary referral centre in Singapore.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Adults who had undergone elective curative surgery for non\u2010metastatic colorectal cancer at least 2 years prior were included. Exclusion criteria were cognitive disease, serious postoperative complications or recurrent cancer. Participants were invited to complete the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires EORTC\u2010QLQ\u2010C30 and QLQ\u2010CR29. Using multiple bivariate analysis, <jats:italic>r<\/jats:italic>\u00a0scores were used to examine relationship trends between QOL domains and survivor sociodemographic and disease\u2010specific characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From February 2017 to July 2019, 400 responses were recorded. Median age and follow\u2010up duration were 64 years (range 32\u201390) and 78 months (interquartile range 49\u2013113) respectively. Patients who had Stage III cancer had better overall QOL scores compared to Stage I\/II. Rectal (vs. colon) cancer negatively influenced sexual health and gastrointestinal function, but did not appear to affect overall QOL. Amongst our cohort, 57% (<jats:italic>n<\/jats:italic>\u00a0=\u00a0129) of men and 43% (<jats:italic>n<\/jats:italic>\u00a0=\u00a075) of women were sexually active. Markers of socioeconomic status, including employment, education and housing type, were found to significantly impact perception of various aspects of QOL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Knowledge of factors which influence well\u2010being can identify individuals who may benefit from tailored management strategies. Regular patient\u2013doctor contact may play a role in building and maintaining positive perspectives of cancer survivors. Normative data should be obtained from local populations to facilitate future comparative research.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.15768","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T15:47:45Z","timestamp":1623080865000},"page":"2348-2360","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Long\u2010term quality of life, sexual health and gastrointestinal function following colorectal cancer resection in an Asian cohort"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8287-6812","authenticated-orcid":false,"given":"Isaac","family":"Seow\u2010En","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Singapore General Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4077-9664","authenticated-orcid":false,"given":"Aik Yong","family":"Chok","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Singapore General Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3020-2108","authenticated-orcid":false,"given":"David Bruce","family":"Matchar","sequence":"additional","affiliation":[{"name":"Programme in Health Services and Systems Research Duke\u2010NUS Medical School Singapore City Singapore"},{"name":"Department of Medicine Duke University Medical School Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9458-6097","authenticated-orcid":false,"given":"Sungwon","family":"Yoon","sequence":"additional","affiliation":[{"name":"Programme in Health Services and Systems Research Duke\u2010NUS Medical School Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8293-4493","authenticated-orcid":false,"given":"Dawn Qingqing","family":"Chong","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology National Cancer Centre Singapore Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0771-5063","authenticated-orcid":false,"given":"Emile Kwong\u2010Wei","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Singapore General Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,27]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"National Registry of Diseases Office.Singapore Cancer Registry Annual Registry Report 2015. 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