{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:24:04Z","timestamp":1783949044202,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010358","name":"KV Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010358","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate whether intramesocolic plane dissection assessed on fresh specimens by the pathologist is a risk factor for recurrence after complete mesocolic excision for sigmoid cancer when compared with mesocolic plane dissection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Single\u2010centre study based on prospectively registered data on patients undergoing resection for UICC stage I\u2013III sigmoid colon adenocarcinoma during the period 2010\u20132017. The patients were stratified into either an intramesocolic plane group or a mesocolic plane group. Primary outcome was risk of recurrence after 4.2\u2009years using inverse probability treatment weighting and competing risk analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of a total of 332 patients, two were excluded as the specimen was assessed as muscularis propria plane, 237 (72%) specimens were deemed as mesocolic and 93 (28%) as intramesocolic. The 4.2\u2010year cumulative incidence of recurrence after inverse probability treatment weighting was 14.9% (10.4\u201319.3) in the mesocolic group compared with 9.4% (3.7\u201315.0) in the intramesocolic group, thus the absolute risk difference between the mesocolic plane and intramesocolic plane was 5.5% (\u221212.5\u20131.6; <jats:italic>p<\/jats:italic>\u00a0=\u20090.13) in favour of the intramesocolic group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intramesocolic plane dissection was not a risk factor for recurrence after complete mesocolic excision for sigmoid cancer when compared with mesocolic plane dissection. No difference in risk of local recurrence, death before recurrence, and in overall survival after 4.2\u2009years was observed between the two groups. With less than 1% of the specimens deemed as muscularis propria plane dissection, the classification appears unusable for the risk prediction of sigmoid colon cancer.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16125","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T14:15:26Z","timestamp":1648476926000},"page":"943-953","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Plane of mesocolic dissection as predictor of recurrence after complete mesocolic excision for sigmoid colon cancer: A cohort study"],"prefix":"10.1111","volume":"24","author":[{"given":"Sara","family":"Sakjah","sequence":"first","affiliation":[{"name":"Department of Surgery Copenhagen University Hospital \u2013 North Zealand  Hiller\u00f8d Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Science University of Copenhagen  Copenhagen 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