{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:10:26Z","timestamp":1789233026384,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T00:00:00Z","timestamp":1661212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aetiology of anal fistula has not been fully clarified. One of the causes of anal fistulas may be the markedly deep crypts that characterize the primary openings. We developed subcutaneous incision of the fistula tract and internal sphincterotomy (SIFT\u2010IS) to eradicate these deep crypts. The aim of this study was to evaluate outcomes in patients with anal fistula treated with SIFT\u2010IS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective study was performed over a 2\u2010year period. Patients with transsphincteric anal fistula who underwent SIFT\u2010IS were enrolled. The primary endpoint was the anal fistula healing rate at 16\u2009weeks postoperatively. The secondary endpoints were healing time, postoperative complications and clinical continence status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and fifty one patients were enrolled. Primary healing was accomplished in 129 patients (85%). There were 17 patients (11%) with a remnant fistula and five (3%) with a recurrence. The remnant fistulas healed spontaneously at more than 16\u2009weeks postoperatively in seven patients. The median healing time was 6 (3\u201396)\u00a0weeks. Surgical intervention was required in seven patients with a remnant fistula and four with recurrence. At the final follow\u2010up, the wounds had healed in 148 patients (98%). No significant postoperative complications or incontinence were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Subcutaneous incision of the fistula tract and internal sphincterotomy is a promising surgical option for transsphincteric anal fistulas, with a satisfactory healing rate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16297","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T06:42:03Z","timestamp":1660113723000},"page":"1576-1583","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Subcutaneous incision of the fistula tract and internal sphincterotomy (<scp>SIFT\u2010IS<\/scp>): a novel surgical procedure for transsphincteric anal fistula"],"prefix":"10.1111","volume":"24","author":[{"given":"Rikisaburo","family":"Sahara","sequence":"first","affiliation":[{"name":"Proctology Center Makita General Hospital  Tokyo Japan"},{"name":"Nishiarai Coloproctology Clinic  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5806-2982","authenticated-orcid":false,"given":"Michihiro","family":"Koizumi","sequence":"additional","affiliation":[{"name":"Nishiarai Coloproctology Clinic  Tokyo Japan"},{"name":"Department of Gastrointestinal and Hepato\u2010Biliary\u2010Pancreatic Surgery Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Morimoto","sequence":"additional","affiliation":[{"name":"Nishiarai Coloproctology Clinic  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itaru","family":"Kubota","sequence":"additional","affiliation":[{"name":"Nishiarai Coloproctology Clinic  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,23]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7341"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000216"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02054434"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02257781"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235039"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800771033"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102168.1999.01077.x"},{"key":"e_1_2_15_9_1","first-page":"581","article-title":"Total anal sphincter saving technique for fistula\u2010in\u2010ano; 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