{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:39:12Z","timestamp":1769125152923,"version":"3.49.0"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T00:00:00Z","timestamp":1668297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The applicability of laparoscopic D3 oncological resection for splenic flexure cancer (SFC) surgery has not been fully explored due to technical difficulties and variations in surgical procedure. The aim of this work is to describe the feasibility of performing laparoscopic D3 resection in SFC and its impact on long\u2010term survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective study on 47 out of 52 consecutive patients who underwent elective laparoscopic colectomy for SFC from December 2006 until December 2019 at Korea University Anam Hospital was performed. Data on patients\u2019 demographic and clinical features, surgical procedures, intraoperative and postoperative complications, pathological features and follow\u2010up were collected. Categorical data are expressed as frequencies (<jats:italic>n<\/jats:italic>) and percentages (%). Continuous data are expressed as mean\u2009\u00b1\u2009standard deviation and median (range). The Kaplan\u2013Meier test was used to determine the overall survival (OS), progression\u2010free survival (PFS) and disease\u2010free survival (DFS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of patients was 67.0\u2009years (range 27\u201387\u2009years) and 72.3% were men. Ten (21.3%) patients presented with an obstructing tumour and underwent an elective laparoscopic colectomy, while 68.1% of patients presented with Stage II and III disease. The conversion rate was 4.3% and the morbidity rate was 31.9%. There was one postoperative death secondary to splenic infarction and anastomotic leak leading to multi\u2010organ failure. Four deaths occurred due to disease progression during a median follow\u2010up of 63.8\u00a0months. The rate of recurrence was 20%, the 5\u2010year OS was 89.6% and the 5\u2010year PFS was 72.9%. After R0 resection, the 5\u2010year OS was 91.5% and the 5\u2010year DFS was 74.5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Laparoscopic D3 colectomy for SFC is feasible, with an acceptable morbidity and long\u2010term oncological outcome when performed by highly skilled laparoscopic colorectal surgeons with knowledge of the complex anatomy around the splenic flexure. Further randomized trials should be performed to determine the advantage of laparoscopic D3 colectomy over conventional colectomy for SFC.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16387","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T06:28:25Z","timestamp":1666679305000},"page":"431-442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Laparoscopic <scp>D3<\/scp> oncological resection in splenic flexure cancer: Technical details and its impact on long\u2010term survival"],"prefix":"10.1111","volume":"25","author":[{"given":"Siti Mayuha","family":"Rusli","sequence":"first","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"},{"name":"Department of Surgery, Faculty of Medicine Universiti Teknologi MARA  Selangor Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Min","family":"Choo","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6667-9202","authenticated-orcid":false,"given":"Guglielmo Niccol\u00f2","family":"Piozzi","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Cuellar\u2010Gomez","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Jin","family":"Baek","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2181-4279","authenticated-orcid":false,"given":"Jung Myun","family":"Kwak","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4526-5147","authenticated-orcid":false,"given":"Seon Hahn","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Department of Surgery, Korea University Anam Hospital Korea University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,13]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(05)70221\u20107"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000499"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001165"},{"key":"e_1_2_13_5_1","doi-asserted-by":"crossref","unstructured":"Transatlantic Laparoscopically Assisted vs Open Colectomy Trials Study Group.Laparoscopically assisted vs open colectomy for colon cancer: a meta\u2010analysis. 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