{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T06:18:09Z","timestamp":1784269089044,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Little is known about how ileal pouch\u2010anal anastomosis (IPAA) influences anorectal manometric data. This study aimed to clarify temporal changes in anorectal manometric data and faecal incontinence in IPAA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined 32 patients with ulcerative colitis (UC) or familial adenomatous polyposis (FAP) undergoing restorative proctocolectomy with stapled or hand\u2010sewn IPAA. Maximum resting pressure (MRP) and maximum squeezing pressure (MSP) were analysed before and 1\u20133, 6\u20139, and 12\u201324\u2009months after IPAA. Cleveland Clinic Florida\u2010Faecal Incontinence Score (CCF\u2010FIS) was measured 6\u20139 and 12\u201324\u2009months after IPAA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen patients underwent stapled IPAA and 18 patients underwent hand\u2010sewn IPAA. MRP decreased 1\u20133\u00a0months after stapled IPAA (median: 42.3\u2009mmHg vs. 60.0\u2009mmHg at preoperative value, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.039), but recovered afterwards. In hand\u2010sewn IPAA, the median MRP decreased to 29.5\u2009mmHg at 1\u20133\u00a0months after IPAA (baseline: 64.8\u2009mmHg, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), and remained unchanged thereafter. Stapled IPAA did not affect MSP; however, hand\u2010sewn IPAA caused a reduction in the median MSP from 191.3\u2009mmHg to 141.3\u2009mmHg at 1\u20133\u00a0months (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.035), which gradually increased afterwards. The median CCFFIS was 5.5 points at 6\u20139\u00a0months and 2 points at 12\u201324\u2009months after stapled IPAA. The score was high (11 points) at 6\u20139\u00a0months but decreased to 5 points at 12\u201324\u2009months after hand\u2010sewn IPAA (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.022).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We present time trends in functional outcomes of IPAA. MRP showed a transient decrease after stapled IPAA, whereas it remained low after hand\u2010sewn IPAA. CCFFIS was high only at 6\u20139\u00a0months after hand\u2010sewn IPAA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16397","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T17:32:16Z","timestamp":1667323936000},"page":"396-403","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Temporal changes in functional outcomes of stapled and hand\u2010sewn ileal pouch\u2010anal anastomosis for ulcerative colitis and familial adenomatous polyposis"],"prefix":"10.1111","volume":"25","author":[{"given":"Risa","family":"Fukui","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology, Faculty of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7891-5986","authenticated-orcid":false,"given":"Hiroaki","family":"Nozawa","sequence":"additional","affiliation":[{"name":"Department of Surgical 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