{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:53:49Z","timestamp":1747184029206,"version":"3.40.5"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:00:00Z","timestamp":1674518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Patients with inflammatory bowel disease (IBD) may undergo several abdominal surgeries with a risk of incisional hernia repair (IHR). The objectives of this study were to establish the risk of IHR and to analyse predictors of IHR after a first\u2010time abdominal surgery for IBD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This Danish nationwide register\u2010based cohort study (1996\u20132018) followed IBD patients from index operation until the date of IHR. The absolute risk was calculated as the cumulative incidence proportion treating death as a competing risk. Cox proportional hazard regression was used to compare the risk of IHR among different subtypes of IBD and to explore predictors of IHR. IBD subtypes were classified as ulcerative colitis (UC), Crohn's disease (CD) or unclassified IBD (IBD\u2010U).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 10\u00a0130 patients with IBD (UC 3911 [39%]; CD 4210 [41%]; IBD\u2010U 2009 [20%]) underwent either an open or a laparoscopic index operation. The 10\u2010year cumulative incidence of IHR varied between 5.0% and 6.3%, with a significantly higher risk in patients with UC and IBD\u2010U. Patients with UC (75.9%) and IBD\u2010U (91.9%) had more (two or more) abdominal surgeries in the follow\u2010up period compared with CD (51.9%). The risk of IHR increased dramatically with the number of surgeries, although not as markedly if a laparoscopic approach was used. Male sex, age, comorbidity, fascial dehiscence, wound infection and presence of stoma were predictors of IHR for patients with IBD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The long\u2010term risk of IHR was roughly 5%\u20136%, with a higher risk in patients with UC and IBD\u2010U. Open surgical approach and number of previous surgeries were, among other things, important predictors of IHR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16478","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T13:45:46Z","timestamp":1673358346000},"page":"964-975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk of incisional hernia repair in patients with inflammatory bowel disease"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7887-3579","authenticated-orcid":false,"given":"Hans","family":"Lov\u00e9n","sequence":"first","affiliation":[{"name":"Centre for Surgical Science, Zealand University Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rune","family":"Erichsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology Aarhus University 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