{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:20Z","timestamp":1787014040874,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T00:00:00Z","timestamp":1678492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The study aimed to compare 5\u2010year overall survival in a national cohort of patients undergoing curative abdominal resection for colon cancer by minimally invasive surgery (MIS) or by the open (OPEN) technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients diagnosed between 2010 and 2016 in Sweden with pathological Union International Contre le Cancer Stages I\u2013III colon cancer localized in the caecum, ascending colon, hepatic flexure or sigmoid colon and those who underwent curative right sided hemicolectomy, sigmoid resection or high anterior resection by MIS or OPEN were included. Patients were identified in the Swedish Colorectal Cancer Registry from which all data were retrieved. The analyses were performed as intention\u2010to\u2010treat and the relationship between surgical technique (MIS or OPEN) and overall mortality within 5\u2009years was analysed. For the primary research question a non\u2010inferiority hypothesis was assumed with a statistical power of 90%, a one\u2010side type I error of 2.5% and a non\u2010inferiority margin of 2%. For the secondary analyses, multilevel survival regression models with the patients matched by propensity scores were employed, adjusted for patient\u2010 and tumour\u2010related variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 11\u2009605 pathological Union International Contre le Cancer Stages I\u2013III patients were included with 3297 MIS (28.4%) and 8308 OPEN (71.6%) and were followed until 31 December 2020. The primary analysis demonstrated superiority for MIS compared to OPEN. The multilevel survival regression analyses confirmed that 5\u2010year overall survival was higher in MIS with a hazard ratio of 0.874 (95% confidence interval 0.791\u20130.965), and if excluding pT4 the outcome was similar, with a hazard ratio of 0.847 (95% confidence interval 0.756\u20130.948).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This observational study demonstrated that MIS was favourable to OPEN with regard to 5\u2010year overall survival. These results support the use of laparoscopic colon cancer surgery in routine practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.16512","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T03:39:19Z","timestamp":1676000359000},"page":"954-963","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Long\u2010term oncological outcomes for minimally invasive surgery versus open surgery for colon cancer\u2014a population\u2010based nationwide study with a non\u2010inferiority design"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6671-7130","authenticated-orcid":false,"given":"Kaveh Dehlaghi","family":"Jadid","sequence":"first","affiliation":[{"name":"Department of Surgery \u00d6rebro University Hospital  \u00d6rebro Sweden"},{"name":"Department of Surgery, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3552-9153","authenticated-orcid":false,"given":"Yang","family":"Cao","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefin","family":"Petersson","sequence":"additional","affiliation":[{"name":"SSORG\u2014Scandinavian Surgical Outcomes Research Group, Department of Surgery Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"},{"name":"Region V\u00e4stra G\u00f6taland, Department of Surgery Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2221-5881","authenticated-orcid":false,"given":"Annika","family":"Sj\u00f6vall","sequence":"additional","affiliation":[{"name":"Gastrointestinal Oncology and Colorectal Surgery Unit, Department of Pelvic Cancer Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9966-4904","authenticated-orcid":false,"given":"Eva","family":"Angenete","sequence":"additional","affiliation":[{"name":"SSORG\u2014Scandinavian Surgical Outcomes Research Group, Department of Surgery Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"},{"name":"Region V\u00e4stra G\u00f6taland, Department of Surgery Sahlgrenska University Hospital  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4939-4189","authenticated-orcid":false,"given":"Peter","family":"Matthiessen","sequence":"additional","affiliation":[{"name":"Department of Surgery \u00d6rebro University Hospital  \u00d6rebro Sweden"},{"name":"Department of Surgery, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,11]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Cancer Research Fund International. Available from:https:\/\/www.wcrf.org\/cancer\u2010trends\/colorectal\u2010cancer\u2010statistics\/"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1713709"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)41741-7"},{"issue":"3","key":"e_1_2_11_5_1","first-page":"144","article-title":"Minimally invasive colon resection (laparoscopic colectomy)","volume":"1","author":"Jacobs M","year":"1991","journal-title":"Surg Laparosc Endosc"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.3.321"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09290-5"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200212000-00008"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66545-2"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0185-7"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.7758"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31816a9d65"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9135-4"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70310-3"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7160"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-4819-8"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16022"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6158-4"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.142.3.298"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2008.03.011"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.3621"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2013.03.002"},{"key":"e_1_2_11_23_1","unstructured":"Nationellt kvalitetsregister f\u00f6rkoloncancer.2010. Available from:https:\/\/cancercentrum.se\/globalassets\/cancerdiagnoser\/tjock\u2010\u2010och\u2010andtarm\u2010anal\/kvalitetsregister\/aldre\u2010rapporter\u2010t.o.m\u20102011\/colon2010_110927.pdf"},{"key":"e_1_2_11_24_1","unstructured":"Swedish Colorectal Cancer Registry (SCRCR).2020. Available from:https:\/\/skr.se\/en\/kvalitetsregister\/hittaregister\/registerarkiv\/tjockochandtarmscancer.44565.html"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2018.1529425"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-12-106"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.13280"},{"key":"e_1_2_11_29_1","unstructured":"Swedish Regional Cancer Center (RCC) website. Available from:https:\/\/statistik.incanet.se\/kolorektal\/rektum\/"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-017-0442-1"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/insr.12214"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16204"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.16512","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/codi.16512","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.16512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T07:15:50Z","timestamp":1692429350000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.16512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,11]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1111\/codi.16512"],"URL":"https:\/\/doi.org\/10.1111\/codi.16512","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,11]]},"assertion":[{"value":"2022-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}