{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:16:55Z","timestamp":1792289815058,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to assess if laparoscopic\u2010assisted transversus abdominis plane (TAP) block (L\u2010TAPB) is as efficient as ultrasound\u2010guided TAP block (U\u2010TAPB) in postoperative pain control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In all, 112 patients scheduled for elective laparoscopic colon resection from February 2018 to December 2021 at two Swiss hospitals were included and randomized in a 1:1 ratio before surgery with either L\u2010TAPB or U\u2010TAPB. The primary end\u2010point was the non\u2010inferiority of the L\u2010TAPB compared to U\u2010TAPB with regard to the total opioid consumption within the first 24\u2009h after surgery. Data regarding patients' characteristics, opioid consumption, pain on the visual analogue scale, operative and anaesthesia induction time, complications and length of stay were collected and analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010five patients were allocated to the L\u2010TAPB and fifty\u2010seven to the U\u2010TAPB. No significant difference was found in the overall dose of opioids within 24\u2009h, and the non\u2010inferiority of the L\u2010TAPB was confirmed. There were almost twice as many patients in the L\u2010TAPB group requesting opioid reserves compared to the U\u2010TAPB group (54.5% vs. 29.8%, <jats:italic>P<\/jats:italic>\u2009=\u20090.008). The anaesthesia induction time was significantly longer in the U\u2010TAPB group (17\u2009\u00b1\u200911\u2009min vs. 23\u2009\u00b1\u200912\u2009min, <jats:italic>P<\/jats:italic>\u2009=\u20090.014). For all other variables (pain on the visual analogue scale, opioid consumption, need of epidural analgesia, operating time, postoperative complications and hospital stay) no statistically significant difference between the L\u2010TAPB and the U\u2010TAPB groups was noted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results showed the non\u2010inferiority of the laparoscopic delivery compared to ultrasound\u2010guided administration of the TAP block, with the advantage of not affecting anaesthesia times.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study registration number<\/jats:title><jats:p>2017\u201002017 CE 3294, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> identifier NCT04575233.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16689","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T04:36:02Z","timestamp":1690864562000},"page":"1921-1928","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Laparoscopic versus ultrasound\u2010guided transversus abdominis plane block in colorectal surgery: a non\u2010inferiority, multicentric randomized double\u2010blinded clinical trial"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3519-0505","authenticated-orcid":false,"given":"Davide","family":"La\u00a0Regina","sequence":"first","affiliation":[{"name":"Department of Surgery Bellinzona e Valli Regional Hospital, EOC  Bellinzona Switzerland"},{"name":"Faculty of Biomedical Sciences Universit\u00e0 della Svizzera Italiana  Lugano 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Hospital, EOC  Bellinzona Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0574-4442","authenticated-orcid":false,"given":"Edoardo","family":"Tasciotti","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Bellinzona e Valli Regional Hospital, EOC  Bellinzona Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2887-5955","authenticated-orcid":false,"given":"Roberto","family":"Dossi","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Bellinzona e Valli Regional Hospital, EOC  Bellinzona Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8194-282X","authenticated-orcid":false,"given":"Dimitri","family":"Christoforidis","sequence":"additional","affiliation":[{"name":"Faculty of Biomedical Sciences Universit\u00e0 della Svizzera Italiana  Lugano Switzerland"},{"name":"Department 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