{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:54:55Z","timestamp":1792176895414,"version":"4.4.0"},"reference-count":148,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T00:00:00Z","timestamp":1701734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014231","name":"European Society of Coloproctology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014231","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The primary aim of the European Society of Coloproctology (ESCP) Guideline Development Group (GDG) was to produce high\u2010quality, evidence\u2010based guidelines for the management of cryptoglandular anal fistula with input from a multidisciplinary group and using transparent, reproducible methodology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Previously published methodology in guideline development by the ESCP has been replicated in this project. The guideline development process followed the requirements of the AGREE\u2010S tool kit. Six phases can be identified in the methodology. Phase one sets the scope of the guideline, which addresses the diagnostic and therapeutic management of perianal abscess and cryptoglandular anal fistula in adult patients presenting to secondary care. The target population for this guideline are healthcare practitioners in secondary care and patients interested in understanding the clinical evidence available for various surgical interventions for anal fistula. Phase two involved formulation of the GDG. The GDG consisted of 21 coloproctologists, three research fellows, a radiologist and a methodologist. Stakeholders were chosen for their clinical and academic involvement in the management of anal fistula as well as being representative of the geographical variation among the ESCP membership. Five patients were recruited from patient groups to review the draft guideline. These patients attended two virtual meetings to discuss the evidence and suggest amendments. In phase three, patient\/population, intervention, comparison and outcomes questions were formulated by the GDG. The GDG ratified 250 questions and chose 45 for inclusion in the guideline. In phase four, critical and important outcomes were confirmed for inclusion. Important outcomes were pain and wound healing. Critical outcomes were fistula healing, fistula recurrence and incontinence. These outcomes formed part of the inclusion criteria for the literature search. In phase five, a literature search was performed of MEDLINE (Ovid), PubMed, Embase (Ovid) and the Cochrane Database of Systematic Reviews by eight teams of the GDG. Data were extracted and submitted for review by the GDG in a draft guideline. The most recent systematic reviews were prioritized for inclusion. Studies published since the most recent systematic review were included in our analysis by conducting a new meta\u2010analysis using Review manager. In phase six, recommendations were formulated, using grading of recommendations, assessment, development, and evaluations, in three virtual meetings of the GDG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In seven sections covering the diagnostic and therapeutic management of perianal abscess and cryptoglandular anal fistula, there are 42 recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is an up\u2010to\u2010date international guideline on the management of cryptoglandular anal fistula using methodology prescribed by the AGREE enterprise.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.16741","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T06:54:39Z","timestamp":1701759279000},"page":"145-196","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":94,"title":["European Society of Coloproctology: Guidelines for diagnosis and treatment of cryptoglandular anal fistula"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1993-2989","authenticated-orcid":false,"given":"Lillian","family":"Reza","sequence":"first","affiliation":[{"name":"St Mark's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8774-5317","authenticated-orcid":false,"given":"Kevin","family":"Gottgens","sequence":"additional","affiliation":[{"name":"M\u00e1xima MC Eindhoven  Eindhoven Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos","family":"Kleijnen","sequence":"additional","affiliation":[{"name":"KSR Ltd &amp; Maastricht University Medical Center (MUMC+) \u2010CAPHRI  Maastricht Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Breukink","sequence":"additional","affiliation":[{"name":"Maastricht University Medical Center (MUMC+)  Maastricht Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter C.","family":"Ambe","sequence":"additional","affiliation":[{"name":"Witten\/Herdecke University  Witten Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Aigner","sequence":"additional","affiliation":[{"name":"St. John of God Hospital  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8803-0874","authenticated-orcid":false,"given":"Erman","family":"Aytac","sequence":"additional","affiliation":[{"name":"Acibadem University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9212-9287","authenticated-orcid":false,"given":"Gabriele","family":"Bislenghi","sequence":"additional","affiliation":[{"name":"University Hospital Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Nordholm\u2010Carstensen","sequence":"additional","affiliation":[{"name":"Bispebjerg University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0704-4068","authenticated-orcid":false,"given":"Hossam","family":"Elfeki","sequence":"additional","affiliation":[{"name":"Mansoura University Hospital  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Gallo","sequence":"additional","affiliation":[{"name":"Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Grossi","sequence":"additional","affiliation":[{"name":"Treviso Regional Hospital  Treviso Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baris","family":"Gulcu","sequence":"additional","affiliation":[{"name":"Medicana Bursa Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3264-7362","authenticated-orcid":false,"given":"Nusrat","family":"Iqbal","sequence":"additional","affiliation":[{"name":"St Mark's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8587-8768","authenticated-orcid":false,"given":"Rosa","family":"Jimenez\u2010Rodriguez","sequence":"additional","affiliation":[{"name":"Virgen del Roc\u00edo University Hospital  Seville Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sezai","family":"Leventoglu","sequence":"additional","affiliation":[{"name":"Gazi University Medical School  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Lisi","sequence":"additional","affiliation":[{"name":"Sant'Eugenio Hospital  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Litta","sequence":"additional","affiliation":[{"name":"Gemelli Hospital Foundation  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Lung","sequence":"additional","affiliation":[{"name":"St Mark's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Millan","sequence":"additional","affiliation":[{"name":"La Fe University and Polytechnic Hospital  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersin","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Medicana Bursa Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene","family":"Sackitey","sequence":"additional","affiliation":[{"name":"St Mark's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0358-2398","authenticated-orcid":false,"given":"Mostafa","family":"Shalaby","sequence":"additional","affiliation":[{"name":"Mansoura University Hospitals  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5256-6167","authenticated-orcid":false,"given":"Jasper","family":"Stijns","sequence":"additional","affiliation":[{"name":"Universitair Ziekenhuis Brussel  Jette Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Tozer","sequence":"additional","affiliation":[{"name":"St Mark's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Elisabeth\u2010TweeSteden Hospital  Tilburg Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,5]]},"reference":[{"key":"e_1_2_21_2_1","unstructured":"ZanottiC Martinez\u2010PuenteC PascualI PascualM HerrerosD.An assessment of the incidence of fistula\u2010in\u2010ano in four countries of the European Union Dami\u00e1n Garc\u00eda\u2010Olmo."},{"issue":"4","key":"e_1_2_21_3_1","first-page":"219","article-title":"Fistula\u2010in\u2010ano in a defined population. Incidence and epidemiological aspects","volume":"73","author":"Sainio P","year":"1984","journal-title":"Ann Chir Gynaecol"},{"key":"e_1_2_21_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i1152"},{"key":"e_1_2_21_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14975"},{"key":"e_1_2_21_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5224.463"},{"key":"e_1_2_21_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13161"},{"key":"e_1_2_21_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800630102"},{"key":"e_1_2_21_9_1","unstructured":"HoYH TanM ChuiCH LeongA EuKW Seow\u2010ChoenF.Randomized controlled trial of primary fistulotomy with drainage alone for perianal abscesses."},{"issue":"7","key":"e_1_2_21_10_1","article-title":"Incision and drainage of perianal abscess with or without treatment of anal fistula","author":"Malik AI","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_21_11_1","unstructured":"TangCL ChewSP Seow\u2010ChoenF.Prospective randomized trial of drainage alone vs. drainage and fistulotomy for acute perianal abscesses with proven internal opening."},{"key":"e_1_2_21_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050209"},{"key":"e_1_2_21_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0429-0"},{"key":"e_1_2_21_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365528708991876"},{"issue":"9","key":"e_1_2_21_15_1","first-page":"539","article-title":"Primary curative incision in the treatment of perianorectal abscess","volume":"35","author":"Li D","year":"1997","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"e_1_2_21_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010020\u201001941\u20109"},{"issue":"8","key":"e_1_2_21_17_1","first-page":"1","article-title":"Internal dressings for healing perianal abscess cavities","volume":"2016","author":"Smith SR","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_21_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0620-1"},{"key":"e_1_2_21_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-014-1231-5"},{"key":"e_1_2_21_20_1","doi-asserted-by":"publisher","DOI":"10.3329\/jafmc.v12i2.41106"},{"key":"e_1_2_21_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10154"},{"key":"e_1_2_21_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znac225"},{"key":"e_1_2_21_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2019.01.015"},{"key":"e_1_2_21_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2017.07.001"},{"key":"e_1_2_21_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e31821cc1f9"},{"issue":"1","key":"e_1_2_21_26_1","first-page":"61","article-title":"Incidence and factors influencing the development of fistula\u2010in\u2010ano after incision and drainage of perianal abscesses","volume":"93","author":"Lohsiriwat V","year":"2010","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_21_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010019\u201002144\u20101"},{"key":"e_1_2_21_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02236900"},{"issue":"1","key":"e_1_2_21_29_1","first-page":"75","article-title":"Natural history of anorectal sepsis","volume":"10","author":"Sahnan K","year":"2016","journal-title":"Roy Soc Med"},{"key":"e_1_2_21_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j475"},{"key":"e_1_2_21_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-017-1645-5"},{"key":"e_1_2_21_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4044"},{"key":"e_1_2_21_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02234601"},{"key":"e_1_2_21_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181d43b7d"},{"key":"e_1_2_21_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e318255ae8a"},{"key":"e_1_2_21_36_1","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v5.i4.123"},{"key":"e_1_2_21_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-006-0829-2"},{"key":"e_1_2_21_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15945"},{"key":"e_1_2_21_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-008-9354-9"},{"key":"e_1_2_21_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2011.197"},{"key":"e_1_2_21_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2019.08.003"},{"key":"e_1_2_21_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800640203"},{"key":"e_1_2_21_43_1","unstructured":"OmmerA HeroldA BergE F\u00fcrstA PostS RuppertR et\u00a0al.German S3 guidelines: anal abscess and fistula (second revised version). Available from:http:\/\/www.awmf.org\/leitlinien\/detail\/ll\/088\u2010005.html"},{"key":"e_1_2_21_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14054"},{"key":"e_1_2_21_45_1","doi-asserted-by":"publisher","DOI":"10.3109\/9781420016192-16"},{"key":"e_1_2_21_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800721211"},{"key":"e_1_2_21_47_1","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2015.76.3.142"},{"key":"e_1_2_21_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-06826-5"},{"key":"e_1_2_21_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)91472-K"},{"key":"e_1_2_21_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11605-9"},{"key":"e_1_2_21_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237196"},{"key":"e_1_2_21_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-007-9309-y"},{"key":"e_1_2_21_53_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2021.20750"},{"key":"e_1_2_21_54_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2333031724"},{"key":"e_1_2_21_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5398"},{"key":"e_1_2_21_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235177"},{"key":"e_1_2_21_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7924.2011.00175.x"},{"key":"e_1_2_21_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006319.pub2"},{"key":"e_1_2_21_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14448"},{"key":"e_1_2_21_60_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000733"},{"key":"e_1_2_21_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010020\u201002385\u20105"},{"key":"e_1_2_21_62_1","unstructured":"AtkinGK MartinsJ TozerP RanchodP PhillipsRKS.For many high anal fistulas lay open is still a good option."},{"key":"e_1_2_21_63_1","unstructured":"TozerP SalaS CianciV KalmarK AtkinGK RahbourG et\u00a0al.Fistulotomy in the tertiary setting can achieve high rates of fistula cure with an acceptable risk of deterioration in continence."},{"key":"e_1_2_21_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000352"},{"key":"e_1_2_21_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010014\u20102072\u2010y"},{"key":"e_1_2_21_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-011-0676-6"},{"key":"e_1_2_21_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13715"},{"key":"e_1_2_21_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13121"},{"key":"e_1_2_21_69_1","doi-asserted-by":"publisher","DOI":"10.11648\/j.js.s.2016040201.14"},{"key":"e_1_2_21_70_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-017-2895-z"},{"key":"e_1_2_21_71_1","doi-asserted-by":"publisher","DOI":"10.9790\/0853\u201017041\u201024245"},{"key":"e_1_2_21_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s1015\u20101\u2010019\u201002023\u20109"},{"key":"e_1_2_21_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010015\u20101323\u20104"},{"key":"e_1_2_21_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2006.01.028"},{"key":"e_1_2_21_75_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4733.18.07617-4"},{"key":"e_1_2_21_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00346220"},{"key":"e_1_2_21_77_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182468c22"},{"key":"e_1_2_21_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010020\u201003759\u20109"},{"key":"e_1_2_21_79_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00529.x"},{"key":"e_1_2_21_80_1","doi-asserted-by":"publisher","DOI":"10.3393\/jksc.2012.28.2.78"},{"key":"e_1_2_21_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20101318.2005.00835.x"},{"key":"e_1_2_21_82_1","doi-asserted-by":"publisher","DOI":"10.4314\/thrb.v15i3.7"},{"key":"e_1_2_21_83_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2019.0057"},{"key":"e_1_2_21_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13120"},{"key":"e_1_2_21_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02234574"},{"key":"e_1_2_21_86_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.13156"},{"key":"e_1_2_21_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-013-1021-z"},{"key":"e_1_2_21_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1479\u2010666X(08)80117\u20105"},{"key":"e_1_2_21_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02070710"},{"key":"e_1_2_21_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s101510100015"},{"key":"e_1_2_21_91_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001045"},{"key":"e_1_2_21_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02081407"},{"key":"e_1_2_21_93_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-014-1186-0"},{"key":"e_1_2_21_94_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1730039"},{"key":"e_1_2_21_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010021\u201002461\u20104"},{"key":"e_1_2_21_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010005\u20100220\u20107"},{"key":"e_1_2_21_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs5.50129"},{"key":"e_1_2_21_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-017-2779-7"},{"key":"e_1_2_21_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.03.009"},{"key":"e_1_2_21_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2019.09.012"},{"key":"e_1_2_21_101_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000194"},{"key":"e_1_2_21_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2011.10.025"},{"key":"e_1_2_21_103_1","doi-asserted-by":"publisher","DOI":"10.1159\/000512652"},{"key":"e_1_2_21_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-011-0769-2"},{"key":"e_1_2_21_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.08.582"},{"key":"e_1_2_21_106_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5905-2"},{"key":"e_1_2_21_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-011-0726-0"},{"key":"e_1_2_21_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-017-1621-0"},{"key":"e_1_2_21_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-020-02165-1"},{"key":"e_1_2_21_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15148"},{"key":"e_1_2_21_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-019-02077-9"},{"key":"e_1_2_21_112_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-015-1282-9"},{"key":"e_1_2_21_113_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000067"},{"key":"e_1_2_21_114_1","first-page":"142","article-title":"Closure of fistula tract with FiLaC[TM] laser as a sphincter\u2010preserving method in anal fistula treatment\/anal Fistul Tedavisinde Sfinkter Koruyucu Yontem Olarak FiLaC[TM] Lazer Yontemiyle Fistul Traktinin Kapatilmasi","volume":"27","author":"Donmez T","year":"2017","journal-title":"Turk J Colorectal Dis"},{"key":"e_1_2_21_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-020-02332-4"},{"key":"e_1_2_21_116_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001628"},{"key":"e_1_2_21_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-018-1885-z"},{"key":"e_1_2_21_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14504"},{"key":"e_1_2_21_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6613"},{"key":"e_1_2_21_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e318206043e"},{"key":"e_1_2_21_121_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i26.3279"},{"key":"e_1_2_21_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10549"},{"key":"e_1_2_21_123_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02902.x"},{"key":"e_1_2_21_124_1","doi-asserted-by":"publisher","DOI":"10.1080\/13645706.2017.1282521"},{"key":"e_1_2_21_125_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000831"},{"key":"e_1_2_21_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ciresp.2018.02.003"},{"issue":"2","key":"e_1_2_21_127_1","first-page":"74","article-title":"Use of the OVESCO OTSC\u00ae proctology clip for closure of fistula\u2010in\u2010ano at Wits Donald Gordon medical Centre \u2010 a single Centre experience","volume":"58","author":"Grossberg SJ","year":"2020","journal-title":"S Afr J Surg"},{"key":"e_1_2_21_128_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-015-1284-7"},{"key":"e_1_2_21_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2146-5"},{"key":"e_1_2_21_130_1","doi-asserted-by":"publisher","DOI":"10.1080\/13645706.2018.1521837"},{"key":"e_1_2_21_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12762"},{"key":"e_1_2_21_132_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.02056.x"},{"key":"e_1_2_21_133_1","first-page":"186350","article-title":"Staged mucosal advancement flap versus staged fibrin sealant in the treatment of complex perianal fistulas","volume":"2011","author":"Hagen SJ","year":"2011","journal-title":"Gastroenterol Res Pract"},{"key":"e_1_2_21_134_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14760"},{"issue":"3","key":"e_1_2_21_135_1","first-page":"2021","article-title":"Platelet rich plasma InjectionVersus ligating inter\u2010sphincteric fistulous tract for Management of High Trans\u2010sphincteric Peri\u2010anal Fistula","volume":"8","author":"Helmy A","year":"2021","journal-title":"Eur J Mol Clin Med"},{"key":"e_1_2_21_136_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010019\u201004480\u2010x"},{"key":"e_1_2_21_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.07.012"},{"key":"e_1_2_21_138_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819ece3e"},{"key":"e_1_2_21_139_1","doi-asserted-by":"publisher","DOI":"10.1177\/1553350618808120"},{"key":"e_1_2_21_140_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-018-0743-8"},{"key":"e_1_2_21_141_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20101318.2009.02087.x"},{"key":"e_1_2_21_142_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15696"},{"key":"e_1_2_21_143_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010003\u20100016\u20106"},{"key":"e_1_2_21_144_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001416"},{"key":"e_1_2_21_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2019.11.008"},{"key":"e_1_2_21_146_1","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12231"},{"key":"e_1_2_21_147_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640620907570"},{"key":"e_1_2_21_148_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-017-1978-4"},{"key":"e_1_2_21_149_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-31802011000200014"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.16741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T01:42:47Z","timestamp":1706319767000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.16741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,5]]},"references-count":148,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/codi.16741"],"URL":"https:\/\/doi.org\/10.1111\/codi.16741","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,5]]},"assertion":[{"value":"2023-04-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}