{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:17:37Z","timestamp":1790223457778,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T00:00:00Z","timestamp":1705276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002706","name":"AFA F\u00f6rs\u00e4kring","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002706","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016406","name":"Doktor Felix Neuberghs Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016406","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005009","name":"Stiftelsen Assar Gabrielssons Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007687","name":"Svenska L\u00e4kares\u00e4llskapet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007687","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014197","name":"Stiftelsen Mary von Sydows, f\u00f6dd Wijk, donationsfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005689","name":"G\u00f6teborgs L\u00e4kares\u00e4llskap","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005689","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this work was to assess the effect of a short\u2010term, home\u2010based exercise intervention before and after colorectal cancer surgery on 12\u2010month physical recovery within a previously reported randomized control trial (RCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>PHYSSURG\u2010C is an RCT in six participating hospitals in Sweden. Patients aged \u226520\u2009years planned for elective colorectal cancer surgery were eligible. The intervention consisted of unsupervised moderate\u2010intensity physical activity 2\u2009weeks preoperatively and 4\u2009weeks postoperatively. Usual care was control. The primary outcome measure in PHYSSURG\u2010C was self\u2010assessed physical recovery 4\u2009weeks postoperatively. The predefined long\u2010term follow\u2010up outcomes included: self\u2010assessed physical recovery 12\u2009months postoperatively and reoperations and readmissions 91\u2013365\u2009days postoperatively. The statistical models were adjusted with tumour site (colon or rectum), neoadjuvant therapy (none, radiotherapy or chemo\/radiotherapy) and type of surgery (open or laparoscopic).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 616 participants were available for the 12\u2010month follow\u2010up. Groups were balanced at baseline regarding demographic and treatment variables. There was no effect from the intervention on self\u2010reported physical recovery [adjusted odds ratio (OR) 0.91,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.60], the risk of reoperation (OR 0.97,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.91) or readmission (OR 0.88,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.58).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The pre\u2010 and postoperative unsupervised moderate\u2010intensity exercise intervention had no effect on long\u2010term physical recovery after elective colorectal cancer surgery. There is still not enough evidence to support clinical guidelines on preoperative exercise to improve outcome after colorectal cancer surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.16860","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T01:33:10Z","timestamp":1705368790000},"page":"545-553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Long\u2010term results of a short\u2010term home\u2010based pre\u2010 and postoperative exercise intervention on physical recovery after colorectal cancer surgery (\n                    <scp>PHYSSURG\u2010C<\/scp>\n                    ): a randomized clinical trial"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1946-3529","authenticated-orcid":false,"given":"Aron","family":"Onerup","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Institute of Clinical 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