{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T04:35:19Z","timestamp":1792989319069,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Obstetric anal sphincter injuries (OASIS) occur in approximately 3%\u20136% of vaginal deliveries and are the leading risk factor for late\u2010onset faecal incontinence, which is an underdiagnosed pathology. The aim of this work was to use a validated scoring system to quantify the effect of irritable bowel syndrome (IBS) on the severity of faecal incontinence symptoms after primary repair of major OASIS (Grade IIIb\u2013IV).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A prospective cohort study was performed on all women who underwent primary repair of major OASIS over a 6\u2010year period. They were assessed with ultrasonography within 12\u2009weeks. Two control groups (who did not have OASIS) were women who underwent elective caesarean section and primigravid women. Questionnaires were sent at least 12\u2009months after delivery, or at first consultation for primigravids, which generated the main outcome measures: Cleveland Clinic faecal incontinence severity scores and the presence of IBS based on Rome III criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a total of 211 patients included in the three groups and the mean follow\u2010up time was 26\u2009months after sphincter repair. Ultrasonographic sphincter defects were detected in 37% but did not affect the faecal incontinence score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.47), except in patients with IBS. Within each group, patients with IBS had significantly worse faecal incontinence than those without. Women with both OASIS and IBS had the most severe faecal incontinence scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OASIS has a limited negative effect on faecal incontinence, independent of whether residual ultrasonographic sphincter defects are present. However, the presence of IBS has a significant compounding effect on faecal incontinence in OASIS patients. The effect of IBS on faecal incontinence is also notable in caesarean section patients and primigravids, suggesting that IBS is an independent risk\u2010factor that should have its place in predelivery assessment and counselling.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.16862","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:39:00Z","timestamp":1705451940000},"page":"508-514","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Irritable bowel syndrome worsens faecal incontinence after primary repair of major obstetric anal sphincter injuries"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3808-0774","authenticated-orcid":false,"given":"Mina","family":"Sarofim","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Royal North Shore Hospital  Sydney New South Wales Australia"},{"name":"School of Medicine University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelie","family":"Slaar","sequence":"additional","affiliation":[{"name":"Department of Radiology Dirksland Ziekenhuis  Hoorn The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Dermout","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Zaans Medisch Centrum  Zaandam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"den\u00a0Boer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Zaans Medisch Centrum  Zaandam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Engel","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Royal North Shore Hospital  Sydney New South Wales Australia"},{"name":"School of Medicine University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2893-4"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.02.041"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000514"},{"issue":"6","key":"e_1_2_13_5_1","first-page":"193","article-title":"Editorial: obstetrical perineal injury and anal incontinence","volume":"5","author":"Sultan AH","year":"1999","journal-title":"J Patient Saf Risk 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