{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T06:18:10Z","timestamp":1784269090329,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of this study is to assess US operative trends and outcomes of ulcerative colitis (UC) patients undergoing total proctocolectomy with ileal pouch\u2212anal anastomosis (TPC\u2010IPAA) or completion proctectomy with IPAA (CP\u2010IPAA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult UC patients who underwent TPC\u2010IPAA or CP\u2010IPAA were analysed retrospectively using the 2016\u20132020 American College of Surgeons National Surgical Quality Improvement Program database. Factors associated with 30\u2010day overall and serious morbidity were identified using multivariable logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1696 patients were identified, with 958 patients (56.5%) undergoing TPC\u2010IPAA and 738 (43.5%) undergoing CP\u2010IPAA. A greater proportion of TPC\u2010IPAAs were performed each year (except in 2019) compared to CP\u2010IPAAs over the study period (<jats:italic>P<\/jats:italic> trend &lt;0.001). Unadjusted analysis showed comparable rates of overall (20.8% vs. 24.4%, <jats:italic>P<\/jats:italic>\u2009=\u20090.076) and serious morbidity (14.3% vs. 12.7%, <jats:italic>P<\/jats:italic>\u2009=\u20090.352) between TPC\u2010IPAA and CP\u2010IPAA patients. Robotic TPC\u2010IPAA had no differences in complications compared to laparoscopic and open approaches. Robotic CP\u2010IPAA had higher anastomotic leak rates and longer hospital length of stay compared to laparoscopic and open approaches. Obesity was associated with increased odds of overall and serious morbidity for patients who underwent TPC\u2010IPAA. Steroid\/immunosuppressive therapy was associated with increased odds of overall and serious morbidity for patients who underwent CP\u2010IPAA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Obese patients should be informed of their increased morbidity risk and offered counselling on weight loss prior to surgery when feasible. Patients on steroid\/immunosuppressive therapy within 30\u2009days preoperatively should not undergo CP\u2010IPAA or should delay surgery until they can be safely off those medications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16891","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T04:09:52Z","timestamp":1706846992000},"page":"497-507","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["National trends and outcomes of total proctocolectomy and completion proctectomy ileal pouch\u2212anal anastomosis procedures for ulcerative colitis"],"prefix":"10.1111","volume":"26","author":[{"given":"Sophia Y.","family":"Chen","sequence":"first","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon N.","family":"Radomski","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miloslawa","family":"Stem","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy Z.","family":"Done","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Caturegli","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"Department of Surgery Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chady","family":"Atallah","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"Department of Surgery NYU Langone Health  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan E.","family":"Efron","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7712-9628","authenticated-orcid":false,"given":"Bashar","family":"Safar","sequence":"additional","affiliation":[{"name":"Colorectal Research Unit, Department of Surgery Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"Department of Surgery NYU Langone Health  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"StatPearls","author":"Lynch WD","year":"2022"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000030"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i31.4320"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i24.3288"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010018\u201003221\u2010x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamasurg.325"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000002113"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.001610"},{"key":"e_1_2_10_10_1","unstructured":"About ACS\u2010NSQIP. 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