{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:25:13Z","timestamp":1782951913185,"version":"3.54.5"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Venous thromboembolic events (VTEs) are relatively common adverse surgical complications. Extended VTE prophylaxis for 4\u2009weeks is recommended after colorectal cancer surgery, but its use in inflammatory bowel disease surgery lacks high\u2010quality evidence. This retrospective study aimed to assess and characterize VTEs within the first 30\u2009days after ileal pouch\u2013anal anastomosis (IPAA) procedures and subtotal colectomies (STCs) for ulcerative colitis (UC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients who underwent IPAA for UC between 1 January 2017 and 31 December 2021 were included. VTE rates after IPAA, in\u2010hospital or at\u2010home occurrences, utilization of in\u2010hospital thromboprophylaxis, and prescribed anticoagulant treatment were evaluated. Retrospectively, the same variables were analysed if patients of the cohort underwent STC before the IPAA construction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 204 patients underwent IPAA (61.8% men, 73% laparoscopic), with an average hospital stay of 6.8\u2009days. Among them, 116 patients underwent STC prior to IPAA. Thirteen patients (6.3%) experienced VTEs after IPAA, with 76.9% (10\/13) of cases occurring during hospitalization and under adequate thromboprophylaxis. The VTE rate after STC was 10.3% (12\/116), with 58.2% (7\/12) occurring in hospital and under appropriate thromboprophylaxis. No reoperations or mortality were attributed to thrombotic events. The type and duration of anticoagulant treatment varied considerably.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The VTE rate after IPAA for UC was 6.3%, with the majority of events occurring in hospital and under adequate thromboprophylaxis. These findings suggest that routine use of extended VTE prophylaxis in our cohort may not be supported. Further research is needed to clarify the optimal VTE prophylaxis strategy for inflammatory bowel disease surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.16912","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T04:58:10Z","timestamp":1708405090000},"page":"726-733","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Is extended venous thromboprophylaxis required in patients undergoing ileal pouch procedure for <scp>ulcerative colitis<\/scp>?"],"prefix":"10.1111","volume":"26","author":[{"given":"Javier","family":"Gomez","sequence":"first","affiliation":[{"name":"Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelia","family":"Theodosopoulos","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"MacRae","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mantaj S.","family":"Brar","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"de Buck\u00a0van\u00a0Overstraeten","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"O'Connor","sequence":"additional","affiliation":[{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harden","family":"Huang","sequence":"additional","affiliation":[{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0707-5294","authenticated-orcid":false,"given":"Erin","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010014\u20102647\u20105"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.02153.x"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpgasthep0190"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12959-015-0044-2"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31821b98da"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izaa002"},{"key":"e_1_2_15_8_1","first-page":"578","article-title":"Venous thromboembolism prophylaxis in inflammatory bowel disease flare\u2010ups","volume":"32","author":"Kaddourah O","year":"2019","journal-title":"Ann Gastroenterol"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14853"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000982"},{"key":"e_1_2_15_11_1","unstructured":"American College of Surgeons.National Surgical Quality Improvement Program ACS NSQIP\u00ae OPERATIONS MANUAL. Venous thrombosis requiring therapy. [Updated 2022 Jan 01]."},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001189"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010013\u20102336\u20107"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13275"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.16912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T04:54:43Z","timestamp":1750136083000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.16912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,19]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/codi.16912"],"URL":"https:\/\/doi.org\/10.1111\/codi.16912","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,19]]},"assertion":[{"value":"2023-05-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}